In the transformation experiment by Griffith, two strains of an organism was injected into a mouse model. One, he labelled S was a heat-killed but pathogenic strain while the other, R was a non- virulent or non-pathogenic strain. Within 48 hours, the mouse died and only the S strain was obtained from the dead mouse. What conclusions can you derived from this experiment? A. Some of the pathogenic S strains survived, proliferated and subsequently overpowered the R strain. B. The R strains mutated and were converted to a pathogenic S strain. C. The R strains assimilated the DNA from the S strain and were transformed into the S strain. D. The R strain DNA hybridized with the S strain DNA such that the daughter DNA of the new generation of R all contained the S DNA. E. All of these conclusions are possible.
Bacterial Genomics
The study of the morphological, physiological, and evolutionary aspects of the bacterial genome is referred to as bacterial genomics. This subdisciplinary field aids in understanding how genes are assembled into genomes. Further, bacterial or microbial genomics has helped researchers in understanding the pathogenicity of bacteria and other microbes.
Transformation Experiment in Bacteria
In the discovery of genetic material, the experiment conducted by Frederick Griffith on Streptococcus pneumonia proved to be a stepping stone.
Plasmids and Vectors
The DNA molecule that exists in a circular shape and is smaller in size which is capable of its replication is called Plasmids. In other words, it is called extra-chromosomal plasmid DNA. Vectors are the molecule which is capable of carrying genetic material which can be transferred into another cell and further carry out replication and expression. Plasmids can act as vectors.
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