Brenner’s m mutant phages (m1–m6) described inFig. 8.8 were suppressed when grown in suppressor(su−) mutant bacteria; they produced full-length Mproteins that functioned like wild-type M protein.a. What gene do you think was mutant in the su−bacteria?b. When the m− phages were propagated in the su−bacterial strain, not all of the proteins made by themutant m alleles were identical to wild-type Mprotein. How did some of them differ?
Bacterial Genomics
The study of the morphological, physiological, and evolutionary aspects of the bacterial genome is referred to as bacterial genomics. This subdisciplinary field aids in understanding how genes are assembled into genomes. Further, bacterial or microbial genomics has helped researchers in understanding the pathogenicity of bacteria and other microbes.
Transformation Experiment in Bacteria
In the discovery of genetic material, the experiment conducted by Frederick Griffith on Streptococcus pneumonia proved to be a stepping stone.
Plasmids and Vectors
The DNA molecule that exists in a circular shape and is smaller in size which is capable of its replication is called Plasmids. In other words, it is called extra-chromosomal plasmid DNA. Vectors are the molecule which is capable of carrying genetic material which can be transferred into another cell and further carry out replication and expression. Plasmids can act as vectors.
Brenner’s m mutant phages (m1
–m6
) described in
Fig. 8.8 were suppressed when grown in suppressor
(su−) mutant bacteria; they produced full-length M
proteins that functioned like wild-type M protein.
a. What gene do you think was mutant in the su−
bacteria?
b. When the m− phages were propagated in the su−
bacterial strain, not all of the proteins made by the
mutant m alleles were identical to wild-type M
protein. How did some of them differ?
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
