'Gamma-delta' T cells differ from 'alpha-beta' T cells by all of the following except O alpha-beta cells are more commonly found in skin and other tissues, while gamma-delta cells are primarily in lymph nodes. O gamma-delta cells undergo more hypermutation for their receptor genes. gamma-delta cells respond more with non-peptide antigens, especially phospholipids. O production of an effector response occurs more rapidly in alpha-beta T cells.

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