Duchenne muscular dystrophy is a recessive disorder caused by a rare,loss-of-function allele that is located on the X chromosome in humans. Anunaffected woman (i.e., without disease symptoms) who is heterozygousfor the X-linked allele causing Duchenne muscular dystrophy has childrenwith a man with a functional (non-disease-causing) allele. What is theprobability that this couple will have an unaffected son?
Duchenne muscular dystrophy is a recessive disorder caused by a rare,
loss-of-function allele that is located on the X chromosome in humans. An
unaffected woman (i.e., without disease symptoms) who is heterozygous
for the X-linked allele causing Duchenne muscular dystrophy has children
with a man with a functional (non-disease-causing) allele. What is the
probability that this couple will have an unaffected son?
Duchenne muscular dystrophy (DMD) is a quickly progressive type of muscular dystrophy that happens principally in young men. It is brought about by a change (mutation) in a gene, considered the DMD gene that can be acquired in families in an X-linked recessive pattern, however, it regularly happens in individuals from families without a known family background of the condition. People who have DMD have progressive loss of muscle capacity and weakness, which starts in the lower limbs.
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