A man, Penoy, whose sister died in early childhood from a recessive lethal disease marries a woman Esmae, who has the same family history. Because Penoy has survived beyond childhood, he does not have the disease, but he may be a carrier (i.e. heterozygous, as may also be the case with Esmae). What is the probability that their first child will suffer from the disease? [Hint: first calculate the probability that Penoy is heterozygous; then determine the probability that both parents are carriers. Remember that he has survived to adulthood when calculating this probability].

BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)
10th Edition
ISBN:9781305967359
Author:STARR
Publisher:STARR
Chapter14: Human Inheritance
Section: Chapter Questions
Problem 4GP: An allele responsible for Marfan syndrome Section 13.4 is inherited in an autosomal dominant...
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A man, Penoy, whose sister died in early childhood from a recessive lethal disease marries a woman Esmae, who has the same family history. Because Penoy has survived beyond childhood, he does not have the disease, but he may be a carrier (i.e. heterozygous, as may also be the case with Esmae). What is the probability that their first child will suffer from the disease? [Hint: first calculate the probability that Penoy is heterozygous; then determine the probability that both parents are carriers. Remember that he has survived to adulthood when calculating this probability].



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