A man with a specific unusual genetic trait marries an unaffected woman. For each type of inheritance, place the pedigree that would result from the cross. Assume the trait is fully penetrant and rare. Autosomal recessive X-linked recessive Y-linked Autosomal dominant X-linked dominant |Unaffected male |Affected male OUnaffected female Affected female Answer Bank 오모오모
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- A man with a specific unusual genetic trait marries an unaffected woman. For each type of inheritance, place the pedigree that would result from the cross. Assume the trait is fully penetrant and rare. Autosomal recessive X-linked recessive Y-linked Autosomal dominant X-linked dominant |Unaffected male | Affected male OUnaffected female Affected femaleConsider the following pedigree, which traces the inheritance of a single-gene hereditary disease. Only individuals that are either affected or normal are shown. In other words, potential heterozygotes are NOT indicated. Characterize each of the following modes of inheritance as: impossible, unlikely, or probable. Justify your answers: Autosomal dominant Autosomal recessive X-linked dominant X-linked recessive Y linkedCystic fibrosis (CF) is an autosomal recessive condition triggered by the overproduction of stickymucus that clogs the lungs and pancreas. It is a life-threatening disease, but medical advances helpedthe afflicted to live through adulthood. The mother of Claudia died from cystic fibrosis, but her father was normal and never had anyrelative with CF. Her fiancé, Marcus, turned out to be a carrier of the CF allele. What are the genotypes of Claudia and Marcus? Claudia: ________________________ Marcus: _____________________ They planned to have four children. What is the probability that:a. all children will be normal b. at least two will be normal
- Cystic fibrosis (CF) is an autosomal recessive condition triggered by the overproduction of stickymucus that clogs the lungs and pancreas. It is a life-threatening disease, but medical advances helpedthe afflicted to live through adulthood.The mother of Claudia died from cystic fibrosis, but her father was normal and never had anyrelative with CF. Her fiancé, Marcus, turned out to be a carrier of the CF allele. What are the genotypes of Claudia and Marcus? Claudia: ________________________ Marcus: _____________________ They planned to have four children. What is the probability that: a. all children will be normal b. at least two will be normalSickle cell anemia is inherited as an autosomal recessive condition. It also exhibits incomplete dominance in that the heterozygous genotype displays a mild form of the disease known as sickle cell trait while individuals with the homozygous recessive genotype have a severe form of SCA. A man who has severe sickle cell anemia marries a woman who suffers from a mild trait. What is the probabilitu they will have a child with severe SCA?What is the probability they will have a child with mild SCA? What is the probability they will have a normal child? Show ALL work using punnett squares.The following pedigree is for a disease that is completely penetrant. For this question,do not make any assumptions of whether the disease is rare or common in the general population. Khich ƠNE of these modes is NOT possible? T O autosomal dominant X-linked dominant O autosomal recessive O X-linked recessive
- This pedigree shows the segregation of a rare disease in a family. What is the most likely mode of inheritance of this disease? (assume complete penetrance) autosomal recessive autosomal dominant x-linked recessive x-linked dominant maternal imprinting paternal imprintingAttached are three pedigrees. For each trait, considerwhether it is or is not consistent with X-linked recessiveinheritance. In a sentence or two, indicate why or why not.In individuals affected by cystic fibrosis, salt crystals may appear afterperspiration dries up. In addition, the disease causes respiratory disorderswhich can be both debilitating and lethal. It occurs in individuals homozygousfor the recessive gene. Two normal parents had a daughter with thesymptoms of this disease, and a normal son who marries a normal womanwith an afflicted A test (salt concentration in perspiration of heterozygotes ishigher than normal) disclosed that both are indeed carriers of the gene. If thefirst child born to the mating in (b) was defective, what is the probability thatthe 2nd child would also be defective?Express answer in fraction form
- X-linked recessive, carrier mother Unaffected. Carrier mother father X Y XX |Unaffected |Affected I Carrier XY Unaffected Unaffected Carrier daughter Affected son daughter U.S. National Library of Medicine son Color blindedness is a sex-linked trait. If we could see the pedigree chart for several more generations of the family illustrated here, we would expect A) more males to be color blind. B) móre females to be color blind. no females to ever be color blind. D) an equal number of males and females that are color blind.An unaffected man and an unaffected woman mate and have a son affected with Kakamania. Which of the following mechanisms of inheritance can not be ruled out? Choose all that can not be ruled out. All of the mechanisms shown can be ruled out Y-linked X-linked Dominant Autosomal Recessive X-linked Recessive Autosomal DominantIn individuals affected by cystic fibrosis, salt crystals may appear afterperspiration dries up. In addition, the disease causes respiratory disorderswhich can be both debilitating and lethal. It occurs in individuals homozygousfor recessive gene. If 2 normal parents had a daughter with the symptoms ofthis disease, and a normal son, what is the probability that he might be acarrier of the recessive gene?Express answer in fraction form.