In Drosophila, a cross (cross 1) was made between twomutant flies, one homozygous for the recessive mutationbent wing (b) and the other homozygous for the recessivemutation eyeless (e). The mutations e and b are alleles oftwo different genes that are known to be very closelylinked on the tiny autosomal chromosome 4. All the progeny had a wild-type phenotype. One of the female progeny was crossed with a male of genotype b e/b e ; we willcall this cross 2. Most of the progeny of cross 2 were of theexpected types, but there was also one rare female ofwild-type phenotype.a. Explain what the common progeny are expected tobe from cross 2.b. Could the rare wild-type female have arisen by (1)crossing over or (2) nondisjunction? Explain.

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Chapter11: Genome Alterations: Mutation And Epigenetics
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Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...
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In Drosophila, a cross (cross 1) was made between two
mutant flies, one homozygous for the recessive mutation
bent wing (b) and the other homozygous for the recessive
mutation eyeless (e). The mutations e and b are alleles of
two different genes that are known to be very closely
linked on the tiny autosomal chromosome 4. All the progeny had a wild-type phenotype. One of the female progeny was crossed with a male of genotype b e/b e ; we will
call this cross 2. Most of the progeny of cross 2 were of the
expected types, but there was also one rare female of
wild-type phenotype.
a. Explain what the common progeny are expected to
be from cross 2.
b. Could the rare wild-type female have arisen by (1)
crossing over or (2) nondisjunction? Explain.

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