Discuss reuptake and enzymatic degradation (breakdown) in the context of the appropriate neurotransmitters. Please include peer reviewed references.
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Discuss reuptake and enzymatic degradation (breakdown) in the context of the appropriate neurotransmitters. Please include peer reviewed references.
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- Can you give a clear explanations of the introduction for this paper? Please explain as if your presenting a group presentation about this paper introduction.List the key challenges in the biosynthesis phosphatidylcholine.Provide a diagram of the EPH RECEPTOR B2 (EPHB2) structure. Give bioinformatics structure
- Briefly explain the role of acetlycholinesterase inhibitors in impulse transmission processStarting from the situation below, explain the next immediate steps that occur after the agonist ligand binds to the GPCR. Describe what happens in terms of the GTP and the heterotrimeric G protein structure. www www Ligand α В GTP ZAN Y Copyright ©2009 Pearson Education, Inc. GDPInhibitors of acetylcholinesterase, such as edrophonium, are used to treat Alzheimer’s disease. The substrate for acetylcholinesterase is acetylcholine. Structures are attached. What kind of inhibitor is edrophonium? Explain. Can inhibition by edrophonium be overcome in vitro by increasing the substrate concentration? Explain. Does this inhibitor bind reversibly or irreversibly to the enzyme? Explain.
- Ethanol is unusual in that it is freely soluble in both water and lipids. Thus, it has access to all regions of the highly vascularized brain. Although the molecular basis of ethanol action in the brain is not clear, ethanol evidently influences a number of neurotransmitter receptors and ion channels. Suggest a biochemical explanation for the diverse effects of ethanol.Can you please describe the role of G proteins in ligand-activated cellular signal transduction.Please asap
- Why do we need to identify and determine the function of every single molecule involved in cell signalling? provide citations of trusted papers/sites. (no less than 250 words)Synthetic opioids are frequently being used for analgesia, i.e. as pain killers. While morphine or other full agonists such as fentanyl are the strongest pain killers available, partial agonists such as nalorphine or pentazocine are being used in applications requiring something intermediate in strength between morphine and basic painkillers such as aspirin. Considering a situation where both morphine and pentazocine are co-administered, select the TRUE statement(s): A. With increasing concentrations of pentazocine, the percent maximal response for morphine can be reduced to the level of pentazocine. B. The dose-response curve for morphine will shift to the right and its shape will not change (parallel rightward shift). C. The dose-response curve for morphine will shift to the left and its shape will not change (parallel leftward shift). D. The maximal efficacy of morphine alone can be exceeded. E. None of the answers here is correct. Please answer asap and type your answer and…Describe the most important regulatory mechanisms controlling the synthesis and secretion of steroids.