Discuss reuptake and enzymatic degradation (breakdown) in the context of the appropriate neurotransmitters. Please include peer reviewed references.
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Discuss reuptake and enzymatic degradation (breakdown) in the context of the appropriate neurotransmitters. Please include peer reviewed references.
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- Can you give a clear explanations of the introduction for this paper? Please explain as if your presenting a group presentation about this paper introduction.What are all the different ways that the g-protein coupled receptor pathway can be targeted by drugs? Please specify the mechanisms and locations with examples.Provide a diagram of the EPH RECEPTOR B2 (EPHB2) structure. Give bioinformatics structure
- Starting from the situation below, explain the next immediate steps that occur after the agonist ligand binds to the GPCR. Describe what happens in terms of the GTP and the heterotrimeric G protein structure. www www Ligand α В GTP ZAN Y Copyright ©2009 Pearson Education, Inc. GDPInhibitors of acetylcholinesterase, such as edrophonium, are used to treat Alzheimer’s disease. The substrate for acetylcholinesterase is acetylcholine. Structures are attached. What kind of inhibitor is edrophonium? Explain. Can inhibition by edrophonium be overcome in vitro by increasing the substrate concentration? Explain. Does this inhibitor bind reversibly or irreversibly to the enzyme? Explain.Can you please describe the role of G proteins in ligand-activated cellular signal transduction.
- Please asapSynthetic opioids are frequently being used for analgesia, i.e. as pain killers. While morphine or other full agonists such as fentanyl are the strongest pain killers available, partial agonists such as nalorphine or pentazocine are being used in applications requiring something intermediate in strength between morphine and basic painkillers such as aspirin. Considering a situation where both morphine and pentazocine are co-administered, select the TRUE statement(s): A. With increasing concentrations of pentazocine, the percent maximal response for morphine can be reduced to the level of pentazocine. B. The dose-response curve for morphine will shift to the right and its shape will not change (parallel rightward shift). C. The dose-response curve for morphine will shift to the left and its shape will not change (parallel leftward shift). D. The maximal efficacy of morphine alone can be exceeded. E. None of the answers here is correct. Please answer asap and type your answer and…Identify and briefly explain a third possible role of oxytocin that could explain its potential benefit to people with autism. Be sure to include the URL of your source with your work.
- One of the initial symptoms a person can have for COVID-19 is the lost of taste and smell. Give a potential mechanism, including which portion of the reflex arc is being impacted, of how COVID is able to have this impact. Use an online source to support your argument.Briefly explain, in biochemical and behavioral means, how cannabis could be used to reduce symptorns in a patient suffering from post-traumatic stress disorder.Describe the general function and structural features of G-protein-coupled receptors (GPCRs). Be sure to include an explanation of GTPase activating proteins (GAPs) and GDP exchange factors (GEFs) in the context of the GTPase cycle. How are different classes of heterotrimeric G-proteins defined?