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Below is the cDNA (coding DNA) and amino acid sequence Human Insulin: 1 ATGGCCCTGTGGATGCGCCTCCTGCCCCTGCTGGCGCTGCTGGCCCTCTGGGGACCTGAC 1 ATGGCCCTGTGGATGCGCCTCCTGCCCCTGCTGGCGCTGCTGGCCCTCTGGGGACCTGAC 1 60 60 20 61 CCAGCCGCAGCCTTTGTGAACCAACACCTGTGCGGCTCACACCTGGTGGAAGCTCTCTAC 61 CCAGCCGCAGCCTTTGTGAACCAACACCTGTGCGGCTCACACCTGGTGGAAGCTCTCTAC 120 21 PAAAFVNQHLCGSHLVEALY 40 120 121 CTAGTGTGCGGGGAACGAGGCTTCTTCTACACACCCAAGACCCGCCGGGAGGCAGAGGAC 180 121 CTAGTGTGCGGGGAACGAGGCTTCTTCTACACACCCAAGACCCGCCGGGAGGCAGAGGAC 180 41 LVCGERGFFYTPKTRREAED 60 181 CTGCAGGCCTCAGCTTTGTCCCTCTCCTCCTCCACGTCAACCTGGCCAGAGGGTCTGGAC 240 181 CTGCAGGCCTCAGCTTTGTCCCTCTCCTCCTCCACGTCAACCTGGCCAGAGGGTCTGGAC 240 61 LQASALSLSSSTSTWPEGLD 80 241 GCCACAGCCAGGGCACCCCCTGCTTTGGTGGTGACTGCTAATATTGGCCAGGCCGGCGGA 300 241 GCCACAGCCAGGGCACCCCCTGCTTTGGTGGTGACTGCTAATATTGGCCAGGCCGGCGGA 300 81 ATARAPPALVVTANIGQAGG 100 301 TCATCGTCCAGGCAGTTTCGGCAGAGAGCCTTGGGCACCAGTGACTCCCCGGTCCTCTTT 360 301 TCATCGTCCAGGCAGTTTCGGCAGAGAGCCTTGGGCACCAGTGACTCCCCGGTCCTCTTT 360 101 SSSRQFRQRALGTSDSPVLF 120 361 ATCCACTGTCCAGGAGCTGCGGGGACTGCGCAGGGACTAGAGTACAGGGGCCGAAGAGTC 420 361 ATCCACTGTCCAGGAGCTGCGGGGACTGCGCAGGGACTAGAGTACAGGGGCCGAAGAGTC 420 121 IHCPGAAGTAQGLEYRGRRV 140 421 ACCACCGAGCTTGTGTGGGAGGAGGTGGATTCCAGCCCCCAGCCCCAGGGCTCTGAATCG 480 421 ACCACCGAGCTTGTGTGGGAGGAGGTGGATTCCAGCCCCCAGCCCCAGGGCTCTGAATCG 480 141 TTELVWEEVDSSPQPQGSES 160 481 CTGCCAGCTCAGCCCCCTGCCCAGCCTGCCCCACAGCCTGAGCCCCAGCAGGCCAGAGAG 540 481 CTGCCAGCTCAGCCCCCTGCCCAGCCTGCCCCACAGCCTGAGCCCCAGCAGGCCAGAGAG 540 161 LPAQPPAQPAPQPEPQQARE 180 541 CCCAGTCCTGAGGTGAGCTGCTGTGGCCTGTGGCCCAGGCGACCCCAGCGCTCCCAGAAC 600 541 CCCAGTCCTGAGGTGAGCTGCTGTGGCCTGTGGCCCAGGCGACCCCAGCGCTCCCAGAAC 600 181 PSPEVSCCGLWPRRPQRSQN 200 601 TGA 601 TGA 603 603 * +The first 20 amino acids are missing to be filled in later 200 1. Look at the mRNA Map above. a. What do A, C, U, and G represent? 10

Below is the cDNA (coding DNA) and amino acid sequence Human Insulin: 1 ATGGCCCTGTGGATGCGCCTCCTGCCCCTGCTGGCGCTGCTGGCCCTCTGGGGACCTGAC 1 ATGGCCCTGTGGATGCGCCTCCTGCCCCTGCTGGCGCTGCTGGCCCTCTGGGGACCTGAC 1 60 60 20 61 CCAGCCGCAGCCTTTGTGAACCAACACCTGTGCGGCTCACACCTGGTGGAAGCTCTCTAC 61 CCAGCCGCAGCCTTTGTGAACCAACACCTGTGCGGCTCACACCTGGTGGAAGCTCTCTAC 120 21 PAAAFVNQHLCGSHLVEALY 40 120 121 CTAGTGTGCGGGGAACGAGGCTTCTTCTACACACCCAAGACCCGCCGGGAGGCAGAGGAC 180 121 CTAGTGTGCGGGGAACGAGGCTTCTTCTACACACCCAAGACCCGCCGGGAGGCAGAGGAC 180 41 LVCGERGFFYTPKTRREAED 60 181 CTGCAGGCCTCAGCTTTGTCCCTCTCCTCCTCCACGTCAACCTGGCCAGAGGGTCTGGAC 240 181 CTGCAGGCCTCAGCTTTGTCCCTCTCCTCCTCCACGTCAACCTGGCCAGAGGGTCTGGAC 240 61 LQASALSLSSSTSTWPEGLD 80 241 GCCACAGCCAGGGCACCCCCTGCTTTGGTGGTGACTGCTAATATTGGCCAGGCCGGCGGA 300 241 GCCACAGCCAGGGCACCCCCTGCTTTGGTGGTGACTGCTAATATTGGCCAGGCCGGCGGA 300 81 ATARAPPALVVTANIGQAGG 100 301 TCATCGTCCAGGCAGTTTCGGCAGAGAGCCTTGGGCACCAGTGACTCCCCGGTCCTCTTT 360 301 TCATCGTCCAGGCAGTTTCGGCAGAGAGCCTTGGGCACCAGTGACTCCCCGGTCCTCTTT 360 101 SSSRQFRQRALGTSDSPVLF 120 361 ATCCACTGTCCAGGAGCTGCGGGGACTGCGCAGGGACTAGAGTACAGGGGCCGAAGAGTC 420 361 ATCCACTGTCCAGGAGCTGCGGGGACTGCGCAGGGACTAGAGTACAGGGGCCGAAGAGTC 420 121 IHCPGAAGTAQGLEYRGRRV 140 421 ACCACCGAGCTTGTGTGGGAGGAGGTGGATTCCAGCCCCCAGCCCCAGGGCTCTGAATCG 480 421 ACCACCGAGCTTGTGTGGGAGGAGGTGGATTCCAGCCCCCAGCCCCAGGGCTCTGAATCG 480 141 TTELVWEEVDSSPQPQGSES 160 481 CTGCCAGCTCAGCCCCCTGCCCAGCCTGCCCCACAGCCTGAGCCCCAGCAGGCCAGAGAG 540 481 CTGCCAGCTCAGCCCCCTGCCCAGCCTGCCCCACAGCCTGAGCCCCAGCAGGCCAGAGAG 540 161 LPAQPPAQPAPQPEPQQARE 180 541 CCCAGTCCTGAGGTGAGCTGCTGTGGCCTGTGGCCCAGGCGACCCCAGCGCTCCCAGAAC 600 541 CCCAGTCCTGAGGTGAGCTGCTGTGGCCTGTGGCCCAGGCGACCCCAGCGCTCCCAGAAC 600 181 PSPEVSCCGLWPRRPQRSQN 200 601 TGA 601 TGA 603 603 * +The first 20 amino acids are missing to be filled in later 200 1. Look at the mRNA Map above. a. What do A, C, U, and G represent? 10

Principles Of Pharmacology Med Assist
Principles Of Pharmacology Med Assist
6th Edition
ISBN:9781337512442
Author:RICE
Publisher:RICE
Chapter26: Medications Used In Treatment Of Endocrine Disorders
Section: Chapter Questions
Problem 16RQ
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Below is the cDNA (coding DNA) and amino acid sequence Human Insulin: 1 ATGGCCCTGTGGATGCGCCTCCTGCCCCTGCTGGCGCTGCTGGCCCTCTGGGGACCTGAC 1 ATGGCCCTGTGGATGCGCCTCCTGCCCCTGCTGGCGCTGCTGGCCCTCTGGGGACCTGAC 1 60 60 20 61 CCAGCCGCAGCCTTTGTGAACCAACACCTGTGCGGCTCACACCTGGTGGAAGCTCTCTAC 61 CCAGCCGCAGCCTTTGTGAACCAACACCTGTGCGGCTCACACCTGGTGGAAGCTCTCTAC 120 21 PAAAFVNQHLCGSHLVEALY 40 120 121 CTAGTGTGCGGGGAACGAGGCTTCTTCTACACACCCAAGACCCGCCGGGAGGCAGAGGAC 180 121 CTAGTGTGCGGGGAACGAGGCTTCTTCTACACACCCAAGACCCGCCGGGAGGCAGAGGAC 180 41 LVCGERGFFYTPKTRREAED 60 181 CTGCAGGCCTCAGCTTTGTCCCTCTCCTCCTCCACGTCAACCTGGCCAGAGGGTCTGGAC 240 181 CTGCAGGCCTCAGCTTTGTCCCTCTCCTCCTCCACGTCAACCTGGCCAGAGGGTCTGGAC 240 61 LQASALSLSSSTSTWPEGLD 80 241 GCCACAGCCAGGGCACCCCCTGCTTTGGTGGTGACTGCTAATATTGGCCAGGCCGGCGGA 300 241 GCCACAGCCAGGGCACCCCCTGCTTTGGTGGTGACTGCTAATATTGGCCAGGCCGGCGGA 300 81 ATARAPPALVVTANIGQAGG 100 301 TCATCGTCCAGGCAGTTTCGGCAGAGAGCCTTGGGCACCAGTGACTCCCCGGTCCTCTTT 360 301 TCATCGTCCAGGCAGTTTCGGCAGAGAGCCTTGGGCACCAGTGACTCCCCGGTCCTCTTT 360 101 SSSRQFRQRALGTSDSPVLF 120 361 ATCCACTGTCCAGGAGCTGCGGGGACTGCGCAGGGACTAGAGTACAGGGGCCGAAGAGTC 420 361 ATCCACTGTCCAGGAGCTGCGGGGACTGCGCAGGGACTAGAGTACAGGGGCCGAAGAGTC 420 121 IHCPGAAGTAQGLEYRGRRV 140 421 ACCACCGAGCTTGTGTGGGAGGAGGTGGATTCCAGCCCCCAGCCCCAGGGCTCTGAATCG 480 421 ACCACCGAGCTTGTGTGGGAGGAGGTGGATTCCAGCCCCCAGCCCCAGGGCTCTGAATCG 480 141 TTELVWEEVDSSPQPQGSES 160 481 CTGCCAGCTCAGCCCCCTGCCCAGCCTGCCCCACAGCCTGAGCCCCAGCAGGCCAGAGAG 540 481 CTGCCAGCTCAGCCCCCTGCCCAGCCTGCCCCACAGCCTGAGCCCCAGCAGGCCAGAGAG 540 161 LPAQPPAQPAPQPEPQQARE 180 541 CCCAGTCCTGAGGTGAGCTGCTGTGGCCTGTGGCCCAGGCGACCCCAGCGCTCCCAGAAC 600 541 CCCAGTCCTGAGGTGAGCTGCTGTGGCCTGTGGCCCAGGCGACCCCAGCGCTCCCAGAAC 600 181 PSPEVSCCGLWPRRPQRSQN 200 601 TGA 601 TGA 603 603 * +The first 20 amino acids are missing to be filled in later 200 1. Look at the mRNA Map above. a. What do A, C, U, and G represent? 10
Transcribed Image Text:Below is the cDNA (coding DNA) and amino acid sequence Human Insulin: 1 ATGGCCCTGTGGATGCGCCTCCTGCCCCTGCTGGCGCTGCTGGCCCTCTGGGGACCTGAC 1 ATGGCCCTGTGGATGCGCCTCCTGCCCCTGCTGGCGCTGCTGGCCCTCTGGGGACCTGAC 1 60 60 20 61 CCAGCCGCAGCCTTTGTGAACCAACACCTGTGCGGCTCACACCTGGTGGAAGCTCTCTAC 61 CCAGCCGCAGCCTTTGTGAACCAACACCTGTGCGGCTCACACCTGGTGGAAGCTCTCTAC 120 21 PAAAFVNQHLCGSHLVEALY 40 120 121 CTAGTGTGCGGGGAACGAGGCTTCTTCTACACACCCAAGACCCGCCGGGAGGCAGAGGAC 180 121 CTAGTGTGCGGGGAACGAGGCTTCTTCTACACACCCAAGACCCGCCGGGAGGCAGAGGAC 180 41 LVCGERGFFYTPKTRREAED 60 181 CTGCAGGCCTCAGCTTTGTCCCTCTCCTCCTCCACGTCAACCTGGCCAGAGGGTCTGGAC 240 181 CTGCAGGCCTCAGCTTTGTCCCTCTCCTCCTCCACGTCAACCTGGCCAGAGGGTCTGGAC 240 61 LQASALSLSSSTSTWPEGLD 80 241 GCCACAGCCAGGGCACCCCCTGCTTTGGTGGTGACTGCTAATATTGGCCAGGCCGGCGGA 300 241 GCCACAGCCAGGGCACCCCCTGCTTTGGTGGTGACTGCTAATATTGGCCAGGCCGGCGGA 300 81 ATARAPPALVVTANIGQAGG 100 301 TCATCGTCCAGGCAGTTTCGGCAGAGAGCCTTGGGCACCAGTGACTCCCCGGTCCTCTTT 360 301 TCATCGTCCAGGCAGTTTCGGCAGAGAGCCTTGGGCACCAGTGACTCCCCGGTCCTCTTT 360 101 SSSRQFRQRALGTSDSPVLF 120 361 ATCCACTGTCCAGGAGCTGCGGGGACTGCGCAGGGACTAGAGTACAGGGGCCGAAGAGTC 420 361 ATCCACTGTCCAGGAGCTGCGGGGACTGCGCAGGGACTAGAGTACAGGGGCCGAAGAGTC 420 121 IHCPGAAGTAQGLEYRGRRV 140 421 ACCACCGAGCTTGTGTGGGAGGAGGTGGATTCCAGCCCCCAGCCCCAGGGCTCTGAATCG 480 421 ACCACCGAGCTTGTGTGGGAGGAGGTGGATTCCAGCCCCCAGCCCCAGGGCTCTGAATCG 480 141 TTELVWEEVDSSPQPQGSES 160 481 CTGCCAGCTCAGCCCCCTGCCCAGCCTGCCCCACAGCCTGAGCCCCAGCAGGCCAGAGAG 540 481 CTGCCAGCTCAGCCCCCTGCCCAGCCTGCCCCACAGCCTGAGCCCCAGCAGGCCAGAGAG 540 161 LPAQPPAQPAPQPEPQQARE 180 541 CCCAGTCCTGAGGTGAGCTGCTGTGGCCTGTGGCCCAGGCGACCCCAGCGCTCCCAGAAC 600 541 CCCAGTCCTGAGGTGAGCTGCTGTGGCCTGTGGCCCAGGCGACCCCAGCGCTCCCAGAAC 600 181 PSPEVSCCGLWPRRPQRSQN 200 601 TGA 601 TGA 603 603 * +The first 20 amino acids are missing to be filled in later 200 1. Look at the mRNA Map above. a. What do A, C, U, and G represent? 10
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