Below is a segment of RNA, transcribed from a DNA sequence. Provide an example of each kind of mutation and explain what will happen to the organism. You may choose which base to alter. Please provide the new amino acid sequence with each mutation. 5’ AUGCCUACGGACUGGCCU 3’ (Met/Pro/Thr/Asp/Trp/Pro) Use the following codon chart to help you show the translation of each sequence.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Below is a segment of RNA, transcribed from a DNA sequence. Provide an example of each kind of mutation and explain what will happen to the organism. You may choose which base to alter. Please provide the new amino acid sequence with each mutation. 5’ AUGCCUACGGACUGGCCU 3’ (Met/Pro/Thr/Asp/Trp/Pro) Use the following codon chart to help you show the translation of each sequence.

 

a. Frameshift Mutation :

b. Missense Mutation :

c. Silent Mutation :

d. What is the anticodon sequence of the original amino acid?

The genetic code
First
Second Letter
Third
Letter
U
C
A
G
Letter
phenylalanine
phenylalanine
leucine
serine
tyrosine
tyrosine
stop
stop
histidine
cysteine
cysteine
stop
tryptophan
arginine
arginine
arginine
arginine
serine
U
U
serine
serine
leucine
serine
G
leucine
proline
proline
proline glutamine
proline glutamine
threonine asparagine
threonine asparagine
C
U
leucine
histidine
leucine
A
leucine
G
A
isoleucine
U
isoleucine
serine
C
isoleucine
threonine
lysine
lysine
arginine
arginine
A
start/
threonine
G
methionine
glycine
glycine
glycine
glycine
G
valine
alanine
aspartate
U
valine
alanine
C
aspartate
glutamate
glutamate
valine
alanine
valine
alanine
G
Transcribed Image Text:The genetic code First Second Letter Third Letter U C A G Letter phenylalanine phenylalanine leucine serine tyrosine tyrosine stop stop histidine cysteine cysteine stop tryptophan arginine arginine arginine arginine serine U U serine serine leucine serine G leucine proline proline proline glutamine proline glutamine threonine asparagine threonine asparagine C U leucine histidine leucine A leucine G A isoleucine U isoleucine serine C isoleucine threonine lysine lysine arginine arginine A start/ threonine G methionine glycine glycine glycine glycine G valine alanine aspartate U valine alanine C aspartate glutamate glutamate valine alanine valine alanine G
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