As part of a cancer research project, you have discovered a gene that is mutated in many metastatic tumors. After determining the DNA sequence of this gene, you compare the sequence with those of other genes in the human genome sequence database. Your gene appears to code for an amino acid sequence that resembles sequences found in some serine proteases. Conjecture how your new gene might contribute to the development of highly invasive cancers.

Q: Occurred in her cells? (Unfortunately her parents have passed away.) I think these genes are…

A: CRISPR stands for Clustered regularly interspaced short palindromic repeats. It is a system of…

Q: The rb gene encodes a protein that inhibits E2F, a transcriptionfactor that activates several genes…

A: Abnormal and unnecessary growth of cells termed cancer. Mutations in DNA causes cancer. In the…

Q: Mutations that are not genetically inherited are called (A) If this type of mutation alters genes…

A: DNA  Deoxyribonucleic acid or DNA is a long chain polymer that present inside the nucleus of the DNA…

Q: Several new cancer drugs inhibit the enzymes that either put acetyl groups on histones or take them…

A: Cancer in simple term can be referred to a set of diseases which are caused by the production of an…

Q: The mutation associated with pancreatic cancer in the family was located in an exon of the palladin…

A: Mutation is a change in the sequence of genetic material either due to a mistake in replication or…

Q: Of the following statements related to the function of telomeres, identify which is FALSE.   a.…

A: Telomerase is an RNA-dependent DNA polymerase that helps extend telomeres. the telomeres are the…

Q: A friend of yours who works at a biotechnology start up company has computationally designed three…

A: The application of scientific and technical principles to the processing of the material by…

Q: cell is homozygous for a LOF mutation in the histone acetyltransferase (HAT) gene. Which of the…

A: HAT stands for Histone acetyl transferase. The LOF refers to the loss of function mutation. If a…

Q: Cancer cells removed from a patient's tumor have increased gene expression of several hundred genes…

A: Cancer  Cancer if a kind of disorder which caused by several means like drug, radiation, malfunction…

Q: You are studying cancer progression in mice. Your results show the following pathway in which two…

A: From the given data the observations made are: The experiment is conducted in a nutrient-enriched…

Q: Give the correct DNA template for this bacterial gene segment (GGG UCG ACA CỤC UUU). ***"Please use…

A: Since you have posted a question with multiple sub- parts,we will solve the first three sub-parts…

Q: Would the viral insertion of a proto-oncogene into a region of genomic DNA with non-acetylated…

A: Acetylation reduces the affinity between histones and DNA by removing positive charges. Thus,…

Q: How many of the mutations listed below would lead to excessive cell growth when the cell was either…

A: Excessive growth occurs when a cell continuously divides and when there is no cell cycle arrest. Myc…

Q: Describe error prone polymerases and the process of translesion synthesis (TLS). In regards to tumor…

A: Translesion synthesis (TLS) is a method of overcoming stopped replication in which particular…

Q: A. Which genes could be used to monitor the process of the disease? B.  If you worked for a drug…

A: By collecting mRNA samples from patients over the course of four phases, we may analyze the…

Q: What is cancer? What defects are commonly found in cancer cells? Do all cancer cells have mutations…

A: Cancer is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells…

Q: I am a Physician Scientist and have a patient that presents with colorectal cancer. I decide to…

A: Given the scenario you've described, where a novel SNP leads to a premature stop codon in a gene…

Q: The mutation associated with pancreatic cancer in the family in Figure23.1 was located in an exon of…

A: Mutation is a change in the sequence of genetic material either due to a mistake in replication or…

Q: You are interested in studying a gene called pumper that is important for heart function. The pumper…

A: Chromatin is the region containing gene. Some genes are in open state and some genes are in closed…

Q: From gene expression studies on cancer, you discovered a hypothetical gene called ABCG2 that is…

A: Transgenic approach has been proved to be very useful in studying physiological function of a…

Q: Many of the mutations in cancer samples are not necessarily driver mutations, but rather passenger…

A: Hematologic childhood cancer can develop in any part of the body, including the blood and lymph…

Q: Please answer this question. I mainly want part A, but if you could answer part B as well, I would…

A: Transcription is the process of formation of mRNA from DNA molecule.  Translation is the process of…

Q: duction of checkpoint proteins so nothing prevents the cells from continually moving forward and…

A: A loss-of-function mutation (LOF) is a type of genetic mutation that disrupts a gene's normal…

Q: A partial DNA sequence, a partial MRNA transcript, and part of the CFTR polypeptide in a cystic…

A: Cystic fibrosis is a disesase that damage the cell producing mucus, sweat and other juices.  in…

Q: telomerase inhibitors to treat hepatocellular carcinoma. They test their drugs on the purified…

A: HEPG2 is a cell line exhibiting epithelial-like morphology that was isolated from a hepatocellular…