Answer the questions below based on the following information: You discover a gene called Y. Mutant clones of Y induces ectopic tissue growth, which is similar to that of the hippo mutation. Therefore you suspect Y is a component of the Hippo signaling pathway. You know the following Hippo pathway components: Fat, Expanded, Hippo, Wts, and Yki, and you have both loss of function mutations as well as UAS overexpression constructs to activate each components of the pathway. Which of these Hippo pathway components promote growth and which ones inhibit growth? To carry out a genetic epistasis tests between the Y mutation and Hippo, should you use the UAS-Hippo construct or hippo mutation? How about an epistasis test between the Y mutation and Wts or Yki?
Answer the questions below based on the following information: You discover a gene called Y. Mutant clones of Y induces ectopic tissue growth, which is similar to that of the hippo mutation. Therefore you suspect Y is a component of the Hippo signaling pathway. You know the following Hippo pathway components: Fat, Expanded, Hippo, Wts, and Yki, and you have both loss of function mutations as well as UAS overexpression constructs to activate each components of the pathway. Which of these Hippo pathway components promote growth and which ones inhibit growth? To carry out a genetic epistasis tests between the Y mutation and Hippo, should you use the UAS-Hippo construct or hippo mutation? How about an epistasis test between the Y mutation and Wts or Yki?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Answer the questions below based on the following information:
You discover a gene called Y. Mutant clones of Y induces ectopic tissue growth, which is similar to that of the hippo mutation. Therefore you suspect Y is a component of the Hippo signaling pathway. You know the following Hippo pathway components: Fat, Expanded, Hippo, Wts, and Yki, and you have both loss of function mutations as well as UAS overexpression constructs to activate each components of the pathway.
- Which of these Hippo pathway components promote growth and which ones inhibit growth?
- To carry out a genetic epistasis tests between the Y mutation and Hippo, should you use the UAS-Hippo construct or hippo mutation? How about an epistasis test between the Y mutation and Wts or Yki?
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