20. A patient with asthma is prescribed a bronchodilator that acts as an agonist at beta-2 adrenergic receptors and she immediately begins to breathe easier when jogging. After a couple weeks of treatment, however, she patient could no longer run without an asthma attack. If pharmacodynamic tolerance was the cause, which of the following mechanisms may be involved? a) Decreased beta-2 receptor density b) Increased metabolism of the bronchodilator c) Decreased degradation of adrenaline d) a & b e) b & c
20. A patient with asthma is prescribed a bronchodilator that acts as an agonist at beta-2 adrenergic receptors and she immediately begins to breathe easier when jogging. After a couple weeks of treatment, however, she patient could no longer run without an asthma attack. If pharmacodynamic tolerance was the cause, which of the following mechanisms may be involved? a) Decreased beta-2 receptor density b) Increased metabolism of the bronchodilator c) Decreased degradation of adrenaline d) a & b e) b & c
Chapter10: Reconstitution Of Powdered Drugs
Section: Chapter Questions
Problem 3.7P
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Transcribed Image Text:20. A patient with asthma is prescribed a bronchodilator that acts as an agonist at beta-2 adrenergic receptors
and she immediately begins to breathe easier when jogging. After a couple weeks of treatment, however,
she patient could no longer run without an asthma attack. If pharmacodynamic tolerance was the cause,
which of the following mechanisms may be involved?
a) Decreased beta-2 receptor density
b) Increased metabolism of the bronchodilator
c) Decreased degradation of adrenaline
d) a & b
e) b & c
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