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2. A researcher attempts to repeat the experiment in which genetic engineering was used to transform cells in culture with the Xist gene. When the Xist gene was targeted to chromosome 21 in cells from a person with Down syndrome (trisomy 21), transcription of the copy of chromosome 21 containing Xist was shut down, much like the inactive X chromosome in cells from a normal female. After carrying out the experiment, the researcher measures the level of transcription averaged over a sample of genes in chromosome 21 and, as a control, measures the level of transcription of a sample of genes in chromosome 6. Shown here are several possible outcomes of such an experiment. Type of cell line Normal | 47,+21 1 47,+21 and Xist transformed 2.0 M 1.5 H K L 1.0 0.5 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Biology: How Life Works, Third Edition O 2019 Macmillan Learning Which bar graph suggests that the experiment succeeded (that is, that the Xist gene became inserted into one of the copies of chromosome 21)? Briefly explain your answer. | Level of transcription

2. A researcher attempts to repeat the experiment in which genetic engineering was used to transform cells in culture with the Xist gene. When the Xist gene was targeted to chromosome 21 in cells from a person with Down syndrome (trisomy 21), transcription of the copy of chromosome 21 containing Xist was shut down, much like the inactive X chromosome in cells from a normal female. After carrying out the experiment, the researcher measures the level of transcription averaged over a sample of genes in chromosome 21 and, as a control, measures the level of transcription of a sample of genes in chromosome 6. Shown here are several possible outcomes of such an experiment. Type of cell line Normal | 47,+21 1 47,+21 and Xist transformed 2.0 M 1.5 H K L 1.0 0.5 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Biology: How Life Works, Third Edition O 2019 Macmillan Learning Which bar graph suggests that the experiment succeeded (that is, that the Xist gene became inserted into one of the copies of chromosome 21)? Briefly explain your answer. | Level of transcription

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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2. A researcher attempts to repeat the experiment in which genetic engineering was used to transform cells in culture with the Xist gene. When the Xist gene was targeted to chromosome 21 in cells from a person with Down syndrome (trisomy 21), transcription of the copy of chromosome 21 containing Xist was shut down, much like the inactive X chromosome in cells from a normal female. After carrying out the experiment, the researcher measures the level of transcription averaged over a sample of genes in chromosome 21 and, as a control, measures the level of transcription of a sample of genes in chromosome 6. Shown here are several possible outcomes of such an experiment. Type of cell line Normal | 47,+21 1 47,+21 and Xist transformed 2.0 M 1.5 H K L 1.0 0.5 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Biology: How Life Works, Third Edition O 2019 Macmillan Learning Which bar graph suggests that the experiment succeeded (that is, that the Xist gene became inserted into one of the copies of chromosome 21)? Briefly explain your answer. | Level of transcription
Transcribed Image Text:2. A researcher attempts to repeat the experiment in which genetic engineering was used to transform cells in culture with the Xist gene. When the Xist gene was targeted to chromosome 21 in cells from a person with Down syndrome (trisomy 21), transcription of the copy of chromosome 21 containing Xist was shut down, much like the inactive X chromosome in cells from a normal female. After carrying out the experiment, the researcher measures the level of transcription averaged over a sample of genes in chromosome 21 and, as a control, measures the level of transcription of a sample of genes in chromosome 6. Shown here are several possible outcomes of such an experiment. Type of cell line Normal | 47,+21 1 47,+21 and Xist transformed 2.0 M 1.5 H K L 1.0 0.5 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Biology: How Life Works, Third Edition O 2019 Macmillan Learning Which bar graph suggests that the experiment succeeded (that is, that the Xist gene became inserted into one of the copies of chromosome 21)? Briefly explain your answer. | Level of transcription
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