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14. DNA methyltransferase, an enzyme that methylates DNA, ----. a. is expressed in a higher than normal amount in a tumor cell; its location is nuclear b. , is expressed in a higher than normal amount in a tumor cell; its location is cytoplasmic c. is expressed in a lower than normal amount in a tumor cell; its location is nuclear d. , is expressed in a lower than normal amount in a tumor cell; its location is cytoplasmic 15. In human cancers, a. Rb promoter is hypermethylated b. expression of CDK inhibitors is inhibited c. there is high level of cyclin D-CDK4/6 kinase activity, phosphorylating pRb d. a and b e. a, b and c 16. Cancer causing agents bring about their effect mainly in G1 phase of the cell cycle because ----. a. the cell has just emerged from the quiescent GO phase b. Gl phase is the longest c. All enzymes and cyclins are active in the G1 phase d. Cells respond to their extracellular growth signals during the G1 phase

14. DNA methyltransferase, an enzyme that methylates DNA, ----. a. is expressed in a higher than normal amount in a tumor cell; its location is nuclear b. , is expressed in a higher than normal amount in a tumor cell; its location is cytoplasmic c. is expressed in a lower than normal amount in a tumor cell; its location is nuclear d. , is expressed in a lower than normal amount in a tumor cell; its location is cytoplasmic 15. In human cancers, a. Rb promoter is hypermethylated b. expression of CDK inhibitors is inhibited c. there is high level of cyclin D-CDK4/6 kinase activity, phosphorylating pRb d. a and b e. a, b and c 16. Cancer causing agents bring about their effect mainly in G1 phase of the cell cycle because ----. a. the cell has just emerged from the quiescent GO phase b. Gl phase is the longest c. All enzymes and cyclins are active in the G1 phase d. Cells respond to their extracellular growth signals during the G1 phase

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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14. DNA methyltransferase, an enzyme that methylates DNA, - ---- a. is expressed in a higher than normal amount in a tumor cell; its location is nuclear b.. is expressed in a higher than normal amount in a tumor cell; its location is cytoplasmic c. is expressed in a lower than normal amount in a tumor cell; its location is nuclear d. . is expressed in a lower than normal amount in a tumor cell; its location is cytoplasmic 15. In human cancers, a. Rb promoter is hypermethylated b. expression of CDK inhibitors is inhibited c. there is high level of cyclin D-CDK4/6 kinase activity, phosphorylating pRb d. a and b e. a, b and c 16. Cancer causing agents bring about their effect mainly in G1 phase of the cell cycle because a. the cell has just emerged from the quiescent G0 phase b. Gl phase is the longest c. All enzymes and cyclins are active in the G1 phase d. Cells respond to their extracellular growth signals during the Gl phase
Transcribed Image Text:14. DNA methyltransferase, an enzyme that methylates DNA, - ---- a. is expressed in a higher than normal amount in a tumor cell; its location is nuclear b.. is expressed in a higher than normal amount in a tumor cell; its location is cytoplasmic c. is expressed in a lower than normal amount in a tumor cell; its location is nuclear d. . is expressed in a lower than normal amount in a tumor cell; its location is cytoplasmic 15. In human cancers, a. Rb promoter is hypermethylated b. expression of CDK inhibitors is inhibited c. there is high level of cyclin D-CDK4/6 kinase activity, phosphorylating pRb d. a and b e. a, b and c 16. Cancer causing agents bring about their effect mainly in G1 phase of the cell cycle because a. the cell has just emerged from the quiescent G0 phase b. Gl phase is the longest c. All enzymes and cyclins are active in the G1 phase d. Cells respond to their extracellular growth signals during the Gl phase
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