9. All organisms have the ability to repair DNA damage caused by mutagenic chemicals. To find genes that encode enzymes that repair DNA damage, scientists isolate mutants that have an abnormally high sensitivity to mutagenic chemicals. Suppose that five different true-breeding mutagen sensitive strains of fruit fly Drosophila melanogaster were isolated (mus mutants). Call these strain #1, strain #2, strain #3, strain #4, and strain #5. Complementation tests were performed with all of these strains and the results are given in the table below. A "+" symbol indicates that when the two indicated strains were crossed, the hybrid was wild-type and a "-" symbol indicates that the hybrid was mutagen sensitive. Assume that each strain has a mutation in just one gene. strain 1 strain 2 + strain 3 + strain 1 strain 2 strain 3 strain 4 strain 5 strain 4 + A. Which mutant strains have mutations in the same gene? B. How many different mus genes are represented here? strain 5 + + + +

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9. All organisms have the ability to repair DNA damage caused by mutagenic chemicals. To find genes that encode
enzymes that repair DNA damage, scientists isolate mutants that have an abnormally high sensitivity to mutagenic
chemicals. Suppose that five different true-breeding mutagen sensitive strains of fruit fly Drosophila melanogaster were
isolated (mus mutants). Call these strain #1, strain #2, strain #3, strain #4, and strain #5. Complementation tests were
performed with all of these strains and the results are given in the table below. A "+" symbol indicates that when the two
indicated strains were crossed, the hybrid was wild-type and a "-" symbol indicates that the hybrid was mutagen sensitive.
Assume that each strain has a mutation in just one gene.
strain 1
strain 2
+
strain 3
+
strain 1
strain 2
strain 3
strain 4
strain 5
strain 4
+
A. Which mutant strains have mutations in the same gene?
B. How many different mus genes are represented here?
strain 5
+
+
+
+
-
Transcribed Image Text:9. All organisms have the ability to repair DNA damage caused by mutagenic chemicals. To find genes that encode enzymes that repair DNA damage, scientists isolate mutants that have an abnormally high sensitivity to mutagenic chemicals. Suppose that five different true-breeding mutagen sensitive strains of fruit fly Drosophila melanogaster were isolated (mus mutants). Call these strain #1, strain #2, strain #3, strain #4, and strain #5. Complementation tests were performed with all of these strains and the results are given in the table below. A "+" symbol indicates that when the two indicated strains were crossed, the hybrid was wild-type and a "-" symbol indicates that the hybrid was mutagen sensitive. Assume that each strain has a mutation in just one gene. strain 1 strain 2 + strain 3 + strain 1 strain 2 strain 3 strain 4 strain 5 strain 4 + A. Which mutant strains have mutations in the same gene? B. How many different mus genes are represented here? strain 5 + + + + -
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