11. Mary Alexander studied the effects of radiation on mutation rates in sperm of Drosophila. She irradiated Drosophila Larva with either 3000r (roentgen) or 3975r, collected adult males that developed from the irradiated larva, mated them with normal un-irradiated females and counted the number of mutants. (ML Alexander, 1954, Genetics 39:409-428) Her observations were: Number of offsprings 45,504 49,512 51,159 Number of mutants Group Control Irradiated (3000r) Irradiated (3975r) 71 70 A. Calculate the mutation rate for all 3 groups. B. On the basis of this experiment, does irradiation cause mutations? C. Does the amount of radiation matter? D. At the rate of mutation for 3000r, how many mutants would you get if you had 1,000,000 offsprings?

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**Study on Radiation Effects on Mutation Rates in Drosophila Sperm**

Mary Alexander conducted a study to examine the effects of radiation on mutation rates in the sperm of Drosophila. She exposed Drosophila larvae to either 3000 roentgens (r) or 3975 roentgens (r) of radiation. The adult males that developed from these irradiated larvae were mated with normal, un-irradiated females, and the number of resulting mutants was counted. (ML Alexander, 1954, Genetics 39:409-428)

The observations from her study were as follows:

| Group                   | Number of Offspring | Number of Mutants |
|-------------------------|---------------------|-------------------|
| Control                 | 45,504              | 2                 |
| Irradiated (3000r)      | 49,512              | 71                |
| Irradiated (3975r)      | 51,159              | 70                |

**Questions:**

A. Calculate the mutation rate for all three groups.

B. Based on this experiment, does irradiation cause mutations?

C. Does the amount of radiation matter?

D. At the mutation rate for 3000 roentgens, how many mutants would you expect if you had 1,000,000 offspring?
Transcribed Image Text:**Study on Radiation Effects on Mutation Rates in Drosophila Sperm** Mary Alexander conducted a study to examine the effects of radiation on mutation rates in the sperm of Drosophila. She exposed Drosophila larvae to either 3000 roentgens (r) or 3975 roentgens (r) of radiation. The adult males that developed from these irradiated larvae were mated with normal, un-irradiated females, and the number of resulting mutants was counted. (ML Alexander, 1954, Genetics 39:409-428) The observations from her study were as follows: | Group | Number of Offspring | Number of Mutants | |-------------------------|---------------------|-------------------| | Control | 45,504 | 2 | | Irradiated (3000r) | 49,512 | 71 | | Irradiated (3975r) | 51,159 | 70 | **Questions:** A. Calculate the mutation rate for all three groups. B. Based on this experiment, does irradiation cause mutations? C. Does the amount of radiation matter? D. At the mutation rate for 3000 roentgens, how many mutants would you expect if you had 1,000,000 offspring?
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