15.26) In transamination reactions, a-ketoglutarate is converted to glutamic acid. The other important reaction in amino acid catabolism is oxidative deamination. In the previous problem, and most other transaminase reactions, a-ketoglutarate is converted to glutamic acid (an amino acid). In oxidative deamination, a quaternary ammonium group (-NH3¹) is removed from glutamic acid, thereby producing ammonium (NH4+), NADH, H+ and one other product. Complete the oxidative deamination reaction below by drawing and naming the missing product. NOTE: The a-ketoglutarate that is produced in the reaction is now free to accept a new quaternary ammonium group from another amino acid in a transamination reaction, as illustrated below. an amino acid H NH,C−C CH₂ CH₂ O + glutamic acid (Glu) + H₂O NAD+ NADH + H+ اسلام deaminase NH4+ + O |_i_ C -C-0 CH₂ CH₂ C-O a-ketoglutarate a-ketoglutarate an a-keto acid transamination oxidative deamination NH₂+ glutamic acid

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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Can u help me to explain to me, please? I stuggled. I don't understand The a-ketoglutarate that is produced in
the reaction is now free to accept a new quaternary ammonium group from another amino acid in a transamination reaction.

15.26) In transamination reactions, a-ketoglutarate is converted to glutamic acid. The other important reaction in amino acid
catabolism is oxidative deamination. In the previous problem, and most other transaminase reactions, a-ketoglutarate is
converted to glutamic acid (an amino acid). In oxidative deamination, a quaternary ammonium group (-NH3+) is removed
from glutamic acid, thereby producing ammonium (NH4*), NADH, H+ and one other product. Complete the oxidative
deamination reaction below by drawing and naming the missing product. NOTE: The a-ketoglutarate that is produced in
the reaction is now free to accept a new
quaternary ammonium group from another
amino acid in a transamination reaction, as
illustrated below.
an amino acid
HO
NHC-
CH₂
I
CH₂
glutamic acid (Glu)
+ H₂O
NAD+
NADH + H+
deaminase
NH, +
O
C
CH₂
CH₂
1_0²
a-ketoglutarate
a-ketoglutarate
an a-keto acid
transamination
oxidative
deamination
NH₂+
glutamic acid
Transcribed Image Text:15.26) In transamination reactions, a-ketoglutarate is converted to glutamic acid. The other important reaction in amino acid catabolism is oxidative deamination. In the previous problem, and most other transaminase reactions, a-ketoglutarate is converted to glutamic acid (an amino acid). In oxidative deamination, a quaternary ammonium group (-NH3+) is removed from glutamic acid, thereby producing ammonium (NH4*), NADH, H+ and one other product. Complete the oxidative deamination reaction below by drawing and naming the missing product. NOTE: The a-ketoglutarate that is produced in the reaction is now free to accept a new quaternary ammonium group from another amino acid in a transamination reaction, as illustrated below. an amino acid HO NHC- CH₂ I CH₂ glutamic acid (Glu) + H₂O NAD+ NADH + H+ deaminase NH, + O C CH₂ CH₂ 1_0² a-ketoglutarate a-ketoglutarate an a-keto acid transamination oxidative deamination NH₂+ glutamic acid
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