15.26) In transamination reactions, a-ketoglutarate is converted to glutamic acid. The other important reaction in amino acid catabolism is oxidative deamination. In the previous problem, and most other transaminase reactions, a-ketoglutarate is converted to glutamic acid (an amino acid). In oxidative deamination, a quaternary ammonium group (-NH3¹) is removed from glutamic acid, thereby producing ammonium (NH4+), NADH, H+ and one other product. Complete the oxidative deamination reaction below by drawing and naming the missing product. NH₁ H O T || C-C-O + H₂O CH₂ CH₂ glutamic acid (Glu) NAD+ NADH + H+ اسلام deaminase NH₂+ + C O CH₂ CH₂ 1_0² a-ketoglutarate NOTE: The a-ketoglutarate that is produced in the reaction is now free to accept a new quaternary ammonium group from another amino acid in a transamination reaction, as illustrated below. an amino acid a-ketoglutarate an a-keto acid transamination oxidative deamination NH₂+ glutamic acid

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15.26) In transamination reactions, a-ketoglutarate is converted to glutamic acid. The other important reaction in amino acid
catabolism is oxidative deamination. In the previous problem, and most other transaminase reactions, a-ketoglutarate is
converted to glutamic acid (an amino acid). In oxidative deamination, a quaternary ammonium group (-NH3*) is removed
from glutamic acid, thereby producing ammonium (NH4+), NADH, H+ and one other product. Complete the oxidative
deamination reaction below by drawing and naming the missing product.
NOTE: The a-ketoglutarate that is produced in
the reaction is now free to accept a new
quaternary ammonium group from another
amino acid in a transamination reaction, as
illustrated below.
an amino acid
+
NH,
H
C-
CH₂
|
O
||
C-O + H₂O
CH₂
|
C-o
glutamic acid (Glu)
NAD+
#
NADH + H+
deaminase
NH4
+
C
I
CH₂
I
CH₂
||
C-o
Ċ-O
||
a-ketoglutarate
a-ketoglutarate
an a-keto acid
transamination
oxidative
deamination
NH₂+
glutamic acid
Transcribed Image Text:15.26) In transamination reactions, a-ketoglutarate is converted to glutamic acid. The other important reaction in amino acid catabolism is oxidative deamination. In the previous problem, and most other transaminase reactions, a-ketoglutarate is converted to glutamic acid (an amino acid). In oxidative deamination, a quaternary ammonium group (-NH3*) is removed from glutamic acid, thereby producing ammonium (NH4+), NADH, H+ and one other product. Complete the oxidative deamination reaction below by drawing and naming the missing product. NOTE: The a-ketoglutarate that is produced in the reaction is now free to accept a new quaternary ammonium group from another amino acid in a transamination reaction, as illustrated below. an amino acid + NH, H C- CH₂ | O || C-O + H₂O CH₂ | C-o glutamic acid (Glu) NAD+ # NADH + H+ deaminase NH4 + C I CH₂ I CH₂ || C-o Ċ-O || a-ketoglutarate a-ketoglutarate an a-keto acid transamination oxidative deamination NH₂+ glutamic acid
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