When alanine undergoes transamination with oxaloacetate, alanine is first converted to alpha-keto acid. The enzyme uses PLP as a cofactor. Suggest a mechanism for this conversion starting with Schiff base PLP-ENZ. Remember to name the resulting alpha-keto acid.

Q: Pyridoxal phosphate acts as an electron sink, stabilizing carbanionic intermediates. What other…

A: Pyridoxal phosphate is necessary for a variety of processes in human metabolism, most notably in the…

Q: Serum blood of a patient with dislipoproteinemia type 1 has milky appearance even in fasting. If…

A: Dyslipoproteinemia is also known as dyslipidemia, which means the abnormal concentration of…

Q: which staments are false

A: Note: Due to the length of the question and the fact that it combines numerous concepts and…

Q: What is the second step in the scientific method?

A: The scientific method is the procedure or experimental technique which are employed in science. It…

Q: D) What are the different substrate specificities of elastase, trypsin, and chymotrypsin? And, why,…

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Q: Mucins found on adenocarcinoma cells carry O-glycans terminated with sialic acids (such as the…

A: Mucins are proteoglycans with many carbohydrate moieties glycosylated to the protein. The type of…

Q: In some metalloproteins such as haemoglobin and some metalloenzymes, the Fe2+ metal is not bound to…

A: Metalloproteins are proteins that contain a specific type of metal ion or metal-containing cofactor…

Q: Explain briefly why ammonia toxicity can result from the consumption of an arginine-deficient diet.…

A: Ammonia is the metabolic waste of protein metabolism. Excessive ammonia is toxic to the human body;…

Q: Considering the general structure of penicillins, how are they rendered ineffective?   Select…

A: Penicillin is an antibiotic that inhibits the formation of peptidoglycan cross-links of the…

Q: Mercuric ion and methanol are inhibitors of alcohol dehydrogenase. Explain.

A: Alcohol (ADH) dehydrogenase is an enzyme that helps in the interconversion of alcohol into ketones…

Q: Which amino acid is an ideal substrate for the oxidative deamination reaction?

A: Oxidative deamination is a type of deamination that happens largely in the liver and results in the…

Q: An individual with an argininosuccinase deficiency is administered benzoate and arginine. This…

A: Argininosuccinase deficiency is a condition where the cells are devoid of an important enzyme i.e.…

Q: What is the oxidation state of sulfur in SO42?

A: Oxidation number, also called as oxidation state is the total number of electrons which an atom…

Q: For answer (a) regarding the last row of compounds, why is the -CH-(CH3)2 not also responsible for…

A: Proteases are enzymes that cleave peptide bonds that link two amino acid residues together.…

Q: Why is D-glucose (dextrose), given intravenously to patients rather than sucrose?

A: In case of weakness sugar molecules are given intravenously and sometimes drugs are also dissolved…

Q: Transamination reactions typically involve which of the following (select all that apply)? O…

A: NOTE: The options are labeled as 1, 2, 3, 4, 5, and 6. Amino acids are the building blocks of…

Q: Which of the following statements is not true about the catalytic triad in chymotrypsin?  Group of…

A: The objective of the question is to identify the incorrect statement about the catalytic triad in…

Q: Pyridoxal phosphate acts as an intermediate carrier of amino groups during transamination reactions.…

A: Pyridoxal phosphate is the active form of Vit B6. It is a coenzyme in a variety of enzymatic…

Q: Match each of the enzymes involved in de novo pyrimidine synthesis with the correct description:…

A:

Q: E. coli can convert glutamate to ornithine. Describe the two reactions that do so.

A: In E.coli, the ornithine compound is synthesized from the compound glutamate.

Functional Diversity