12. Consider the following genetically controlled biosynthetic pathway in a hypothetical plant: gene A gene B gene C Enzyme A Enzyme B Enzyme C PO - P1 P2 P3 Protein C Assume that gene A controls the conversion of a white pigment, P0, to another white pigment, P1; the dominant allele A codes for the enzyme necessary to catalyze this conversion, but the recessive allele a codes for a defective enzyme (with no activity). Gene B controls the conversion of the white pigment, P1, to a pink pigment, P2; again, the dominant allele, B, produces the enzyme necessary for the P1 - P2 conversion, but the recessive allele b produces an inactive product. The dominant allele, C, of a third gene codes for an enzyme that catalyzes the conversion of the pink pigment, P2, to a red pigment. P3; its recessive allele, c, produces an altered enzyme with no activity. The dominant allele, D, of a fourth gene produces a gene product that completely inhibits the activity of enzyme C; that is, it blocks the reaction P2 - P3. Its recessive allele, d, produces a defective gene product that does not block the P2 - P3 reaction. Assume that flower color is determined solely by these four genes and that they assort independently (i.e. are located on four different chromosomes). In the F2 of a cross between plants of genotype AAbbCCDD and plants of genotype aaBBccdd, what proportion of the plants would be expected to have: (a) red flowers? (b) pink flowers? (c) white flowers?

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12. Consider the following genetically controlled biosynthetic pathway in a hypothetical
plant:
gene A
gene B
gene C
Enzyme A
Enzyme B
Enzyme C
PO →
P1
P2
P3
Protein C
eme D
Assume that gene A controls the conversion of a white pigment, PO, to another white
pigment, P1; the dominant allele A codes for the enzyme necessary to catalyze this
conversion, but the recessive allele a codes for a defective enzyme (with no activity). Gene
B controls the conversion of the white pigment, P1, to a pink pigment, P2; again, the
dominant allele, B, produces the enzyme necessary for the P1 - P2 conversion, but the
recessive allele b produces an inactive product. The dominant allele, C, of a third gene codes
for an enzyme that catalyzes the conversion of the pink pigment, P2, to a red pigment. P3;
its recessive allele, c, produces an altered enzyme with no activity.
The dominant allele, D, of a fourth gene produces a gene product that completely inhibits the
activity of enzyme C; that is, it blocks the reaction P2 - P3. Its recessive allele, d, produces
a defective gene product that does not block the P2 - P3 reaction.
Assume that flower color is determined solely by these four genes and that they assort
independently (ie. are located on four different chromosomes). In the F2 of a cross between
plants of genotype AAbbCCDD and plants of genotype aaBBccdd, what proportion of the
plants would be expected to have: (a) red flowers? (b) pink flowers? (c) white flowers?
Transcribed Image Text:12. Consider the following genetically controlled biosynthetic pathway in a hypothetical plant: gene A gene B gene C Enzyme A Enzyme B Enzyme C PO → P1 P2 P3 Protein C eme D Assume that gene A controls the conversion of a white pigment, PO, to another white pigment, P1; the dominant allele A codes for the enzyme necessary to catalyze this conversion, but the recessive allele a codes for a defective enzyme (with no activity). Gene B controls the conversion of the white pigment, P1, to a pink pigment, P2; again, the dominant allele, B, produces the enzyme necessary for the P1 - P2 conversion, but the recessive allele b produces an inactive product. The dominant allele, C, of a third gene codes for an enzyme that catalyzes the conversion of the pink pigment, P2, to a red pigment. P3; its recessive allele, c, produces an altered enzyme with no activity. The dominant allele, D, of a fourth gene produces a gene product that completely inhibits the activity of enzyme C; that is, it blocks the reaction P2 - P3. Its recessive allele, d, produces a defective gene product that does not block the P2 - P3 reaction. Assume that flower color is determined solely by these four genes and that they assort independently (ie. are located on four different chromosomes). In the F2 of a cross between plants of genotype AAbbCCDD and plants of genotype aaBBccdd, what proportion of the plants would be expected to have: (a) red flowers? (b) pink flowers? (c) white flowers?
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