...ATC ACC AAA AAC CGC AAC CTG CAC TCG... m allele 5’...ATC ACC AAA AAC TGC AAC CTG CAC TCG... A. Compare these two allele sequences and circle the nucleotides that are different. B. Do you think this change will cause a shift in the codon reading frame? Why or why not? C. Do you think that this change will cause an early stop in translation? Why or why not?
Task #1 Mc1r alleles: In Florida Gulf coast mice, there are two different alleles of the Melanocortin Receptor (Mcr1) gene. The sequence for both alleles is shown below. This is an internal segment of the coding (non-template) sequence of the Mcr1 gene. The reading frame is set and you do not need to find an AUG. M allele 5’...ATC ACC AAA AAC CGC AAC CTG CAC TCG... m allele 5’...ATC ACC AAA AAC TGC AAC CTG CAC TCG... A. Compare these two allele sequences and circle the nucleotides that are different.
B. Do you think this change will cause a shift in the codon reading frame? Why or why not?
C. Do you think that this change will cause an early stop in translation? Why or why not?
Task #2 Flow of information: A codon table is provided above. The 5’ codon
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