. You obtain the DNA sequence of a mutant of a 2-kb gene in which you are interested and it shows base differences at three positions, all in different codons. One is a silent change, but the other two are missense changes (they encode new amino acids). How would you demonstrate that these changes are real mutations and not sequencing errors? (Assume that sequencing is about 99.9 percent accurate.)

Q: Consider the following DNA sequence: CATGTGTAGTCTAAA. Address the followin questions: AWrite the…

A: In DNA,the genes are present.From these genes mRNA is formed by transcription. This mRNA undergoes…

Q: They want to insert a small sequence into the gene which will be read in the same frame, so that it…

A: The expression of a protein occurs in two steps. Transcription: The gene is transcribed by RNA…

Q: 7a. Given the following mutated sequence (with respect to the normal sequence), what TYPE of…

A: DNA is the genetic material present in most of the living organisms. The DNA is made up of 4…

Q: 1、You have a 250 bp DNA sequence from a human protein-coding gene.  What's the best tool to find out…

A: When analyzing DNA sequences and performing tasks such as gene identification and sequence…

Q: Given an artificial mRNA consisting of a repeated dinucleotide (5'... GUGUGUGUGUGU... 3), match the…

A: A codon is a group of three DNA or RNA nucleotides that codes for a particular amino acid or protein…

Q: 1. Write the complementary coding strand sequence 5' GGG ATG TCA CAC ATA TTT 2. Write the mRNA…

A: The coding strand of DNA is the one that contains the instructions for the gene in concern. The…

Q: A team of scientist is interested in the amplification of a specific DNA fragment in a large plasmid…

A: The specific DNA sequence can be amplified by using primers in the polymerase chain reaction or PCR.…

Q: 8a. Given the following mutated sequence (with respect to the normal sequence), what TYPE of…

A: Mutation can be defined as change in nucleotide sequence of a gene. Based on the type of change,…

Q: You obtain the DNA sequence of a mutant of a 2-kb gene in which you are interested and it shows base…

A: the mutation is the change or error that is caused in the chromosome it is of a different type 1.…

Q: When aligning the three sequences (ATGC, AATC, AATG), one can use a 3-D "Manhattan Grid", with each…

A: ANSWER: ATG-C AAT-C AA-TG

Q: . The position of the gene for the protein actin in the haploid fungus Neurospora is known from the…

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: If the mutation causing Tay Sachs disease involves a C to T change at position 4 in the sequence…

A: Gene probes are of three types: gene-specific probes, polymorphic probes and oligonucleotide probes.…

Q: Posttranscriptional modifications include adding a 5’ cap and a 3’ tail removing a 5’ cap and a 3’…

A: The process by which the information contained in a strand of DNA is transcribed into a new molecule…

Q: What is the length in basepairs of these sequences? How many base substitutions are there between…

A: The multiple sequence alignment (MSA) involves the alignment of three or greater than three…

Q: How many base substitutions are there between these sequences? Count ONLY the instances where there…

A: Sequence alignment involves the comparison of sequences of a particular gene from various organisms…

Q: protein. How would the protein produced from sequence #1 differ from the protein produced from…

A: The sequences provided are of a non-coding strand or template strand. mRNA is transcribed…

Q: You want to examine genetic variation in your gene promoter. You sequence DNA from several…

A: Single nucleotide polymorphism; it is a type of genetic variation which can occur throughout a…

Q: As a hobby you propagate a population of worms. You notice that one worm is now clear instead of…

A: Deletions are mutations in which a section of DNA is lost, or deleted. Since protein-coding DNA is…

Q: a. Replicate this sense strand to create a double-stranded DNA helix. Write your answers in CAPS…

A: DNA replication is a phenomenon in which DNA make itself using Enzyme DNA Polymerase . It occurs in…

Q: . The following data represent the base compositions of double-stranded DNA from two different…

A: A gene is the essential physical and functional unit of heredity. They are comprised of DNA…

Q: Now you have the gene sequence. Now you would like to clone it into an expression vector to grow up…

A: Answer. The majority of eukaryotic genes contain non-coding DNA. The genes tend to have a split…

Q: Your advisor, a brilliant bioinformatician, has high regard for your intellect and industry. she…

A: Introduction  A genome is consists of transcriptionally active genes. These genes form mRNA as they…

Genome annotation

The technique of linking biological information to genome sequences is termed genome annotation. Gene annotation is the method of identifying gene locations and coding sections. It helps us understand what these genes are doing in the body through establishing structural characteristics and linking them to the actions of various proteins.