. Cells containing missense mutations in the crp gene(encoding the positive regulator CRP) are Lac−, Mal−,Gal−, etc. To find cells with suppressors of the crpmutation (that is, cells with the crp mutation thatbehave as if they are crp+), cells were screened tofind those that were both Lac+ and Mal+.a. What types of suppressor mutations would youexpect to obtain using this screen compared with ascreen for Lac+ only?b. All suppressors isolated were mutant in the genefor the α-subunit of RNA polymerase. What hypothesis could you propose based on this analysis?

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.