Solutions for FUNDAMENTALS OF BIOCHEMISTRY WPNG 1-SEME
Problem 2E:
2. Name the following nucleotide.
Problem 3E:
3. In many organisms, DNA is modified by methylation. Draw the structure of 5-methylcytosine, a base...Problem 4E:
4. When cytosine is treated with bisulfite, the amino group is replaced with a carbonyl group....Problem 5E:
5. Kinases are enzymes that transfer a phosphoryl group from a nucleoside triphosphate. Which of the...Problem 6E:
6. Kinases are enzymes that transfer a phosphoryl group from a nucleoside triphosphate. Which of the...Problem 7E:
7. A diploid organism with a 45,000-kb haploid genome contains 21% G residues. Calculate the number...Problem 8E:
8. A segment of DNA containing 20 base pairs includes 7 guanine residues. How many adenine residues...Problem 10E:
10. Explain why increasing the NaCl concentration increases the temperature at which the two strands...Problem 11E:
11. An enzyme from the human immunodeficiency virus (HIV, which causes AIDS) can synthesize DNA from...Problem 12E:
12. How many different amino acids could theoretically be encoded by nucleic acids containing four...Problem 13E:
13. The human genome contains thousands of sequences known as small open reading frames, some of...Problem 15E:
15. The recognition sequence for the restriction enzyme TaqI is T?CGA. Indicate die products of the...Problem 16E:
16. Using the data in Table 3-2, identify restriction enzymes that (a) produce blunt ends; (b)...Problem 17E:
17. The 13-Mb genome of the green alga Ostreococcus tauri contains ?8000 genes. Compare the gene...Problem 18E:
18. Describe how to select recombinant clones if a foreign DNA is inserted into the polylinker site...Problem 22E:
22. Why do cDNA libraries derived from different cell types within the same organism differ from...Problem 23CQ:
23. Some RNA molecules me covalently modified by methylation at the N6 position in adenosine...Problem 24CQ:
24. Would the modified nucleoside described in Question 23 be able to participate in standard...Problem 25CQ:
25. Draw the tautomeric form of adenine.
Problem 26CQ:
26. Draw the tautomeric form of cytosine.
Problem 27CQ:
27. The pK value for N1 of adenine is 3.64, whereas the pK value for N1 of guanine is 9.50. Explain...Problem 30CQ:
30. Hypoxanthine can also base-pair with cytosine. Draw the structure of this base pair.
Problem 31CQ:
31. Describe the outcome of a chain-terminator sequencing procedure in which (a) too little ddNTP is...Problem 32CQ:
32. Describe the outcome of a chain-terminator sequencing procedure in which (a) too few primers are...Problem 33CQ:
33. Calculate the number of clones required to obtain with a probability of 0.99 a specific 5-kb...Problem 34CQ:
34. You are attempting to clone a 250-kb segment of mouse DNA in a yeast artificial chromosome. You...Problem 35CQ:
35. Describe the possible outcome of a PCR experiment in which (a) one of the primers is...Problem 36CQ:
36. Describe the possible outcome of a PCR experiment in which (a) there is a single-stranded break...Problem 37CQ:
37. Write the sequences of the two 12-residue primers that could be used to amplify the following...Browse All Chapters of This Textbook
Chapter 1 - Introduction To The Chemistry Of LifeChapter 2 - WaterChapter 3 - Nucleotides, Nucleic Acids, And Genetic InformationChapter 4 - Amino AcidsChapter 5 - Proteins: Primary StructureChapter 6 - Proteins: Three-dimensional StructureChapter 7 - Protein Function: Myoglobin And Hemoglobin, Muscle Contraction, And AntibodiesChapter 8 - CarbohydratesChapter 9 - Lipids And Biological MembranesChapter 10 - Membrane Transport
Chapter 11 - Enzymatic CatalysisChapter 12 - Enzyme Kinetics, Inhibition, And ControlChapter 13 - Biochemical SignalingChapter 14 - Introduction To MetabolismChapter 15 - Glucose CatabolismChapter 16 - Glycogen Metabolism And GluconeogenesisChapter 17 - Citric Acid CycleChapter 18 - Electron Transport And Oxidative PhosphorylationChapter 19 - PhotosynthesisChapter 20 - Lipid MetabolismChapter 21 - Amino Acid MetabolismChapter 22 - Mammalian Fuel Metabolism: Integration And RegulationChapter 23 - Nucleotide MetabolismChapter 24 - Nucleic Acid StructureChapter 25 - Dna Replication, Repair, And RecombinationChapter 26 - Transcription And Rna ProcessingChapter 27 - Protein SynthesisChapter 28 - Regulation Of Gene Expression
Sample Solutions for this Textbook
We offer sample solutions for FUNDAMENTALS OF BIOCHEMISTRY WPNG 1-SEME homework problems. See examples below:
Functional groups are the reactive regions of molecules that are functionalized with these specific...Pictorial presentation: Fig. 1 shows structure of guanine, where the potential hydrogen bond donors...Explanation: The given structure in the diagram is of the nucleoside diphosphate called guanosine...Amino acid is a basic structural unit of a protein. It forms a peptide bond by joining two or more...Explanation: The sequence of amino acids forms primary structure that are linked together by peptide...Fig. 1 shows the cis peptide with groups that experience steric effects. The cis peptide bonds are...Explanation: When fractional saturation is half, it means that the ligand has occupied half of the...Explanation: The formula to calculate the number of stereoisomers in a given carbohydrate is 2n,...Explanation: Trans isomers have a higher melting point compared to cis isomers. It is mainly because...
Explanation: The extracellular concentration of glucose is 5mM = 0.005M. The intracellular...Reason for the correct statement: Option b. is given as, “It increases the rate at which a chemical...Calculation: Given: The nonenzymatic elementary reaction is AàB, where A is the reactant and B is...Hormones are of two types, namely, steroid hormones and peptide hormones. Steroid hormones are lipid...Explanation: Autotrophs possess the capability of synthesizing micronutrients including vitamins and...In glycolysis, 10 steps are involved to convert glucose to pyruvate; out of these, during four...Explanation: Glycogen is broken down when the cell needs to produce ATP from glucose. The enzyme...Explanation: Citric acid cycle is central to the metabolism. Acetyl CoA enters the citric acid cycle...Explanation: The mitochondrion is a cell organelle with outer and inner membrane made of lipid...In plants, the light reactions use light energy to produce adenosine triphosphate (ATP) and...Explanation: The enzyme glycerol kinase acts on the L-glycerol and it forms L-glycerol-3-phosphate....Explanation: ATP is the energy currency of the cell which can be renewed. In a cell when catabolism...The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the...Explanation: The reaction in which aspartate is added to the IMP and adenylosuccinate lyase take...Explanation: Hypoxanthine is a naturally occurring modified form of purine base. Hypoxanthine is...Calculation: Given: The total genome content of E.coli chromosome=4×106 base pairs. The length of...Explanation: Cordycepin is also known as 3ʹ-deoxyadenosine. Adenosine is a cellular purine...Explanation: A 4-nt insertion is the addition of four nucleotides to the sequence. This means that...Explanation: The percentage of single-stranded DNA is plotted as a function of Cot; that is, the...
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