Concept explainers
Interpretation:
The explanation, with the help of a diagram, of the acetylation or phosphorylation of histones that could change their binding affinity with the DNA.
Concept Introduction:
Histones are the basic proteins that are found complexed with the DNA (deoxyribonucleic acid). They help in the packaging of the DNA, and their complex is known as chromatin. There are four types of histones named H2A, H2B, H3, and H4. Two molecules of each of these proteins are joined to form a histone octamer.
The histone octamer with the wrapped DNA is termed as nucleosome, and several nucleosomes connected by H1 histones form the chromatin. The string portion is termed as spacer region. There are about 150 base pairs of DNAs wrapped around one octamer, and the spacer or linking region contains about 30 to 50 base pairs.
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Biochemistry
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- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage Learning