FUND.OF GEN CHEM CHAP 1-13 W/ACCESS
16th Edition
ISBN: 9781323406038
Author: McMurry
Publisher: PEARSON C
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Chapter 6.5, Problem 6.1CIAP
Dietary iron forms a 1:1 complex with hemoglobin (Hb), which is responsible for O2 transport in the body based on the following equation:
How many moles of oxygen could be transported by the hemoglobin complex formed from 8 mg of dietary iron?
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The 2-3 phosphoglycerate (BFG) binds to the central gap formed by the hemoglobin monomers (a2b2) facilitating the reversible release of oxygen. Approximate relationships between BFG concentrations in red blood cells and Pos in hemoglobin are in the table.a) Draw the reaction schemeb) Write the forces that condition the union between hemoglobin and BFG
A 46
1- 1,3-Bisphosphoglycerate (1,3-BPG) is a phosphoryl group donor during the
synthesis of ATP in the reaction:
1,3-BPG + ADP → 3-Phosphoglycerate + ATP
In human erythrocytes, the steady-state concentration of ATP is 2.24 mM, that
of ADP is 0.25 mM, and that of 3-Phosphoglycerate is 0.15 mM. Calculate the
concentration of 1,3-BPG at 25 °C, assuming that the above reaction is at the
Equilibrium in the cell, and that the AG° of the reaction is -18.9 kJ/mol. Use
R=8.315 J/mol.K and show your work.
2- In fact, the above reaction is maintained in a non-Equilibrium steady state in
human erythrocytes; and the AG’ of the reaction is equal to -3.7 kJ/mol in these
conditions. Calculate the concentration of 1,3-BPG at 25 °C in this non-
Equilibrium steady state. Show your work.
Chapter 6 Solutions
FUND.OF GEN CHEM CHAP 1-13 W/ACCESS
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