EBK EXPERIMENTAL ORGANIC CHEMISTRY: A M
6th Edition
ISBN: 9781305687875
Author: Gilbert
Publisher: CENGAGE LEARNING - CONSIGNMENT
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Chapter 6.2, Problem 6E
Interpretation Introduction
Interpretation:
Concept introduction:Diastereomers of
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9) Below is a statin, simvastatin, used for treating high cholesterol. Assign the stereochemical configuration of
the selected tetrahedral carbon chiral centers (R, S or N (not a chiral center)) and the alkene (E, Z or N (not a
stereocenter)) that are indicated by the arrows (note that you do not have to assign the configuration of every
chiral center in the molecule). If the atom in question is not a chiral center or is not a stereocenter circle N for
neither.
RS N
RS N
HO
RS N
I
RS N
RS N
RS N
EZ N
EZ N
What is the thermodynamic product obtained from the addition of 1 equivalent of HBr to 1,3-butadiene?
Stereochemistry in biological molecules is often denoted by the D- and L- convention, instead of the R- and S- configurations
determined by the Cahn-Ingold-Prelog methodology. Historically, the glyceraldehyde enantiomer that rotated plane polarized
light clockwise was arbitrarily designated as D and the other enantiomer was designated as the L configuration.
The D-glyceraldehyde Fischer projection is shown.
D-glyceraldehyde
H
H-
-OH
CH₂OH
Identify which structures are equivalent to the D-configuration.
H
CH₂OH
76.
OH
CH₂OH
H-
-OH
☐
O
H
ОН
-CH₂OH
K
H
H
Incorrect
HOCH2
H
OH
t
H
OH
CH₂OH
K.
Chapter 6 Solutions
EBK EXPERIMENTAL ORGANIC CHEMISTRY: A M
Ch. 6.2 - Prob. 1ECh. 6.2 - Prob. 2ECh. 6.2 - Prob. 3ECh. 6.2 - Prob. 4ECh. 6.2 - Prob. 5ECh. 6.2 - Prob. 6ECh. 6.2 - Prob. 7ECh. 6.2 - Prob. 8ECh. 6.2 - Prob. 9ECh. 6.3 - Prob. 1E
Ch. 6.3 - Prob. 2ECh. 6.3 - Prob. 3ECh. 6.3 - Prob. 4ECh. 6.3 - Prob. 5ECh. 6.3 - Prob. 6ECh. 6.3 - Prob. 7ECh. 6.3 - Prob. 8ECh. 6.3 - Prob. 9ECh. 6.3 - Prob. 10ECh. 6.3 - Prob. 11ECh. 6.3 - Prob. 12ECh. 6.3 - Prob. 13ECh. 6.3 - Prob. 14ECh. 6.3 - Prob. 15ECh. 6.3 - Prob. 16ECh. 6.3 - Prob. 17ECh. 6.3 - Prob. 18ECh. 6.3 - Prob. 19ECh. 6.3 - Prob. 20ECh. 6.4 - Prob. 1ECh. 6.4 - Prob. 2ECh. 6.4 - Prob. 3ECh. 6.4 - Prob. 4ECh. 6.4 - Prob. 5E
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