CAMPBELL BIOLOGY,VOL.II >CUSTOM<
CAMPBELL BIOLOGY,VOL.II >CUSTOM<
17th Edition
ISBN: 9781323803677
Author: Urry
Publisher: PEARSON
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Chapter 42.4, Problem 3CC
Summary Introduction

To explain: The reason behind why nitroglycerin is preferred to relieve chest pain and used to treat heart disease patients.

Concept introduction:

Nitroglycerin is used as a vasodilator that opens blood vessels to improve blood flow. Angina results when there is imbalance between the oxygen supply and oxygen demand without a proportional increase in supply. The process of narrowing of arterioles is known as vasoconstriction. The process of relaxation of arterioles is known as vasodilatation.

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It has beta-2 selective agonist activity. It does not provide cardiac stimulation with its bronchodilatory effect. It has lesser cardiac adverse effects as a selective alpha-1 antagonist. It has a open-piperazine ring which renders it to be less cardiotoxic.
8.

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