
Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Chapter 35, Problem 38CTQ
What are possible treatments for patients with major depression?
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 35 Solutions
Biology 2e
Ch. 35 - Figure 35.3 Which of the following statements is...Ch. 35 - Figure 35.11 Potassium channel blockers, such as...Ch. 35 - Figure 35.26 Which of the following statements is...Ch. 35 - Neurons contain _____ which can receive_____...Ch. 35 - A(n)______neuron has one axon and one____ dendrite...Ch. 35 - Glia that provide myelin for neurons in the brain...Ch. 35 - Meningitis is a viral or bacterial infection of...Ch. 35 - For a neuron to fire an action potential, its...Ch. 35 - After an action potential, the opening of...Ch. 35 - What is the term for protein channels that connect...
Ch. 35 - Which of the following molecules is not involved...Ch. 35 - Thelobe contains the visual cortex frontal...Ch. 35 - Theconnects the two cerebral hemispheres. limbic...Ch. 35 - Neurons in Thecontrol motor reflexes. thalamus...Ch. 35 - Phineas Gage was a 19th century railroad worker...Ch. 35 - Activation of the sympathetic nervous system...Ch. 35 - Where are parasympathetic preganglionic cell...Ch. 35 - ______ is released by motor nerve endings onto...Ch. 35 - Parkinson’s disease is a caused by the...Ch. 35 - __________ medications are often used to treat...Ch. 35 - Strokes are often caused by. neurodegeneration...Ch. 35 - Why is it difficult to identify the cause of many...Ch. 35 - Why do many patients with neurodevelopmentaJ...Ch. 35 - How are neurons similar to other cells? How are...Ch. 35 - Multiple sclerosis causes demyelination of axons...Ch. 35 - Many neurons have only a single axon, but many...Ch. 35 - How does myelin aid propagation of an action...Ch. 35 - What are the main steps in chemical...Ch. 35 - Describe how long-term potentiation can lead to a...Ch. 35 - What methods can be used to determine the function...Ch. 35 - What are the main functions of the spinal cord?Ch. 35 - Alzheimer’s disease involves three of the four...Ch. 35 - What are the main differences between the...Ch. 35 - What are the main functions of the sensory somatic...Ch. 35 - Describe how the sensory-somatic nervous system...Ch. 35 - Scientists have suggested that the autonomic...Ch. 35 - What are the main symptoms of Alzheimer’s disease?Ch. 35 - What are possible treatments for patients with...
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- There is currently a H5N1 cattle outbreak in North America. According to the CDC on Feb 26*: "A multistate outbreak of HPAI A(H5N1) bird flu in dairy cows was first reported on March 25, 2024. This is the first time that these bird flu viruses had been found in cows. In the United States, since 2022, USDA has reported HPAI A(H5N1) virus detections in more than 200 mammals." List and describe two mechanisms that could lead to this H5N1 influenza strain evolving to spread in human: Mechanisms 1: Mechanisms 2: For the mutations to results in a human epidered they would need to change how the virus interacts with the human host. In the case of mutations that may promote an epidemic, provide an example for: a protein that might incur a mutation: how the mutation would change interactions with cells in the respiratory tract (name the receptor on human cells) List two phenotypic consequence from this mutation that would increase human riskarrow_forwardYou have a bacterial strain with the CMU operon: a) As shown in the image below, the cmu operon encodes a peptide (Pep1), as well as a kinase and regulator corresponding to a two-component system. The cmu operon is activated when Pep 1 is added to the growth media. Pep1 is a peptide that when added extracellularly leads to activation of the Cmu operon. Pep1 cmu-kinase cmu-regulator You also have these genetic components in other strains: b) An alternative sigma factor, with a promoter activated by the cmu-regulator, that control a series of multiple operons that together encode a transformasome (cellular machinery for transformation). c) the gene cl (a repressor). d) the promoter X, which includes a cl binding site (and in the absence of cl is active). e) the gene gp (encoding a green fluorescence protein). Using the cmu operon as a starting point, and assuming you can perform cloning to rearrange any of these genomic features, how would you use one or more of these to modify the…arrow_forwardYou have identified a new species of a Gram-positive bacteria. You would like to screen their genome for all proteins that are covalently linked to the cell wall. You have annotated the genome, so that you identified all the promoters, operons, and genes sequences within the operons. Using these features, what would you screen for to identify a set of candidates for proteins covalently linked to the bacterial cell wall.arrow_forward
- Below is a diagram from a genomic locus of a bacterial genome. Each arrow represents a coding region, and the arrowheads indicate its orientation in the genome. The numbers are randomly assigned. Draw the following features on the diagram, and explain your rationale for each feature: 10 12 合會會會會長 6 a) Expected transcriptions, based on known properties of bacterial genes and operons. How many proteins are encoded in each of the transcripts? b) Location of promoters (include rationale) c) Location of transcriptional terminators (include rationale) d) Locations of Shine-Dalgarno sequences (include rationale)arrow_forwardSample excuse letter in school class for the reasons of headaches and dysmenorrhea caused by menstrual cyclearrow_forwardHow do the muscles on the foot work to balance on an ice skate, specifically the triangle of balance and how does it change when balancing on an ice skate? (Refer to anatomy, be specific)arrow_forward
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