Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 3, Problem 8P
When a hydrophobic substance like a hydrocarbon is dissolved in water, a clathrate cage of ordered water molecules is formed about it (see Figure 2.14). If we consider only the effects on water, what do you expect the sign of
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In an experiment, a 0.001 (mole fraction) solution of polysaccharide in water is made and is placed in the compartment A (see Figure below). Compartment B is filled with pure water. The two compartments are separated by a porous semi-permeable membrane that allows the exchange of water molecules between the two compartments, but not that of the larger polysaccharide molecules
a) Show that the chemical potential of water in compartment A is lower than that in compartment B by 2.48 J/mol.
b) As a result of this chemical potential difference, water molecules will move from compartment B to compartment A. This causes the pressure in compartment A, relative to that in B, to increase. How would this affect the chemical potential of water in compartment B? When would the diffusion of water from B to A cease (i.e. equilibrium is achieved)?
c) Using your answer to part (b), work out the difference between the pressure in compartment A and B when…
Solution A contains 100 mmol/L glucose and Solution B contains 50 mmol/L NaCl. Assume that gNaCl is 2.0, σglucose is 0.5, and σNaCl is 0.8. If a semipermeable membrane separates the two solutions, what is the direction of water flow across the membrane?
What, if anything, is wrong with the following statement: “When NaCl is dissolved in water, the water molecules closest to the ions will tend to preferentially orient themselves so that their oxygen atoms face the sodium ions and face away from the chloride ions”? Explain your answer.
Chapter 3 Solutions
Biochemistry: Concepts and Connections (2nd Edition)
Ch. 3 - Prob. 1PCh. 3 - Given the following reactions and their...Ch. 3 - The decomposition of crystalline N2O5...Ch. 3 - The oxidation of glucose to CO2 and water is a...Ch. 3 - Prob. 5PCh. 3 - In another key reaction in glycolysis,...Ch. 3 - Assume that some protein molecule, in its folded...Ch. 3 - When a hydrophobic substance like a hydrocarbon is...Ch. 3 - It is observed that as temperature is increased,...Ch. 3 - Suppose a reaction has Ho and So values...
Ch. 3 - Prob. 11PCh. 3 - Prob. 12PCh. 3 - Prob. 13PCh. 3 - Undergoing moderate activity, an average person...Ch. 3 - The major difference between a protein molecule in...Ch. 3 - Prob. 16PCh. 3 - Prob. 17PCh. 3 - Consider the degradation of glucose to pyruvate by...Ch. 3 - a. Consider the malate dehydrogenase reaction,...Ch. 3 - Bovine ribonuclease folds with Ho = -280 kJmol-1...
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- A researcher prepares 100 mL of aqueous solution containing 0.1 g of a protein. The researcher then uses an experimental apparatus ,where he notes that, at room temperature (300K) and atmospheric pressure (101.325 kPa), distilled water flows naturally into the solution compartment. However, when he applies an extra pressure of 1000 Pa he observes that the flow of distilled water ceases and the system is in balance. Calculate the molar mass of this protein, in kDa (1 Da = 1 g/ mol); Why does the flow of distilled water cease with the application of the pressure of 1000 Pa? Explain in terms of potential chemicals. %3Darrow_forwardIf the noncovalent interactions are so weak in a water environment, how can they possibly be important for holding molecules together in cells?arrow_forwardThe pH vs charge graph for a triprotic amino acid is shown below. Please answer the following questions about the amino acid. 2 1.5 1 0.5 -0.5 -1 4 6. 8 10 12 14 pH a. Which of the following triprotic amino acids is this? [ Select ] b. What is the isoelectric point? (Please select the appropriate range in which the isoelectric point falls) (Hint - look up the pka values in the pKa table for amino acids, which was in video one of today's lecture) [ Select ] c. What form of this amino acid dominates at a pH of 8? Please select the correct form for each ionizable group. Alpha amino [ Select ] Alpha carboxyl [ Select ] R [ Select ] Net Chargearrow_forward
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