Introduction to General, Organic and Biochemistry
11th Edition
ISBN: 9781285869759
Author: Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher: Cengage Learning
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Chapter 29, Problem 29.35P
Interpretation Introduction
Interpretation:
The coenzyme that reduces CO2 in the calvin cycle is to be interpreted.
Concept introduction:
The multi-step cyclic process for the reduction of CO2 by NADPH, is known as calvin cycle.
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Learning Goal:
As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.
The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).
Part A - Difference in binding free eenergies
Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol.
The margin of error is 2%.
Part B - Compare difference in free energy to the thermal energy
Divide the…
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Chapter 29 Solutions
Introduction to General, Organic and Biochemistry
Ch. 29 - Prob. 29.1PCh. 29 - Prob. 29.2PCh. 29 - Prob. 29.3PCh. 29 - Prob. 29.4PCh. 29 - Prob. 29.5PCh. 29 - Prob. 29.6PCh. 29 - Prob. 29.7PCh. 29 - Prob. 29.8PCh. 29 - Prob. 29.9PCh. 29 - Prob. 29.10P
Ch. 29 - Prob. 29.11PCh. 29 - Prob. 29.12PCh. 29 - Prob. 29.13PCh. 29 - Prob. 29.14PCh. 29 - Prob. 29.15PCh. 29 - Prob. 29.16PCh. 29 - Prob. 29.17PCh. 29 - Prob. 29.18PCh. 29 - Prob. 29.19PCh. 29 - Prob. 29.20PCh. 29 - Prob. 29.21PCh. 29 - Which of these fatty acids can be synthesized by...Ch. 29 - Prob. 29.23PCh. 29 - Prob. 29.24PCh. 29 - Prob. 29.25PCh. 29 - Prob. 29.26PCh. 29 - Prob. 29.27PCh. 29 - Prob. 29.28PCh. 29 - Prob. 29.29PCh. 29 - Prob. 29.30PCh. 29 - Prob. 29.31PCh. 29 - Prob. 29.32PCh. 29 - Prob. 29.33PCh. 29 - Prob. 29.34PCh. 29 - Prob. 29.35PCh. 29 - Prob. 29.36PCh. 29 - Prob. 29.37PCh. 29 - Prob. 29.38PCh. 29 - Prob. 29.39PCh. 29 - Prob. 29.40PCh. 29 - Prob. 29.41PCh. 29 - Prob. 29.42PCh. 29 - Prob. 29.43PCh. 29 - Prob. 29.44PCh. 29 - Prob. 29.45PCh. 29 - Prob. 29.46PCh. 29 - Prob. 29.47PCh. 29 - Prob. 29.48PCh. 29 - Prob. 29.49PCh. 29 - Prob. 29.50PCh. 29 - Prob. 29.51PCh. 29 - Prob. 29.52PCh. 29 - Prob. 29.53PCh. 29 - Prob. 29.54PCh. 29 - Prob. 29.55PCh. 29 - Prob. 29.56PCh. 29 - Prob. 29.57PCh. 29 - Prob. 29.58PCh. 29 - Prob. 29.59PCh. 29 - 29-60 How does the energy source differ in...Ch. 29 - Prob. 29.61PCh. 29 - A vegan diet is one that excludes all animal...Ch. 29 - Prob. 29.63PCh. 29 - Prob. 29.64PCh. 29 - Prob. 29.65PCh. 29 - Prob. 29.66PCh. 29 - Prob. 29.67PCh. 29 - Prob. 29.68P
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