Introduction to General, Organic and Biochemistry
11th Edition
ISBN: 9781285869759
Author: Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher: Cengage Learning
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Chapter 29, Problem 29.28P
Interpretation Introduction
Interpretation:
The importance of HMG-CoA reductase in the synthesis of cholesterol is to be interpreted.
Concept introduction:
The synthesis of cholesterol begins with the sequential condensation of three acetyl CoA molecules.
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Fatty acids and triglycerides are an important source of nutrition and a dense form
of stored energy. Digestion of fats yields more energy per gram than digestion of
carbohydrates.
Each turn on the B-oxidation spiral results in the formation of a new acetyl COA
molecule. This molecule can then be used to generate more energy in
A) fatty acid synthesis
B) ketolysis
C) glycolysis
D) tricarboxylic acid cycle
E) oxidative phosphorylation
The glycolysis pathway is shown. Place the enzymes used in each of the ten labeled steps of the pathway. Be sure to scroll
down completely until pyruvate is formed.
triosephosphate isomerase
phosphofructokinase-1
glucose-6-phosphate
fructose-6-phosphate
fructose-1,6-biphosphate
ADP
ATP
ADP
hexokinase
ATP
glucose
dihydroxyacetonephosphate
phosphohexose isomerase
Answer Bank
What am I doing wrong?
aldolase
glyceraldehyde-3-phosphate
glyceraldehyde-3-phosphate
dehydrogenase
phosphoglycerate kinase
phosphoglycerate mutase
enolase
pyruvate kinase
NAD* + HOPO₂²
NADH+H*
1,3-bisphosphoglycerate
ADP
ATP
3-phosphoglycerate
Z-phosphoglycerate
phosphoenolpyruvate
ADP
ATP
pyruvate
The glycolysis pathway is shown. Place the enzymes used in each of the ten labeled steps of the pathway. Be sure to scroll
down completely until pyruvate is formed.
glucose-6-phosphate
fructose-6-phosphate
fructose-1,6-biphosphate
ADP
ATP
ADP
ATP
glucose
dihydroxyacetonephosphate
glyceraldehyde-3-phosphate
1,3-bisphosphoglycerate
ADP
ATP
3-phosphoglycerate
2-phosphoglycerate
phosphoenolpyruvate
ADP
ATP
pyruvate
Answer Bank
phosphoglycerate mutase
hexokinase
phosphohexose isomerase
triosephosphate isomerase
phosphofructokinase-1
pyruvate kinase
phosphoglycerate kinase
aldolase
enolase
glyceraldehyde-3-phosphate
dehydrogenase
NAD + HOPO3²-
NADH+H*
Chapter 29 Solutions
Introduction to General, Organic and Biochemistry
Ch. 29 - Prob. 29.1PCh. 29 - Prob. 29.2PCh. 29 - Prob. 29.3PCh. 29 - Prob. 29.4PCh. 29 - Prob. 29.5PCh. 29 - Prob. 29.6PCh. 29 - Prob. 29.7PCh. 29 - Prob. 29.8PCh. 29 - Prob. 29.9PCh. 29 - Prob. 29.10P
Ch. 29 - Prob. 29.11PCh. 29 - Prob. 29.12PCh. 29 - Prob. 29.13PCh. 29 - Prob. 29.14PCh. 29 - Prob. 29.15PCh. 29 - Prob. 29.16PCh. 29 - Prob. 29.17PCh. 29 - Prob. 29.18PCh. 29 - Prob. 29.19PCh. 29 - Prob. 29.20PCh. 29 - Prob. 29.21PCh. 29 - Which of these fatty acids can be synthesized by...Ch. 29 - Prob. 29.23PCh. 29 - Prob. 29.24PCh. 29 - Prob. 29.25PCh. 29 - Prob. 29.26PCh. 29 - Prob. 29.27PCh. 29 - Prob. 29.28PCh. 29 - Prob. 29.29PCh. 29 - Prob. 29.30PCh. 29 - Prob. 29.31PCh. 29 - Prob. 29.32PCh. 29 - Prob. 29.33PCh. 29 - Prob. 29.34PCh. 29 - Prob. 29.35PCh. 29 - Prob. 29.36PCh. 29 - Prob. 29.37PCh. 29 - Prob. 29.38PCh. 29 - Prob. 29.39PCh. 29 - Prob. 29.40PCh. 29 - Prob. 29.41PCh. 29 - Prob. 29.42PCh. 29 - Prob. 29.43PCh. 29 - Prob. 29.44PCh. 29 - Prob. 29.45PCh. 29 - Prob. 29.46PCh. 29 - Prob. 29.47PCh. 29 - Prob. 29.48PCh. 29 - Prob. 29.49PCh. 29 - Prob. 29.50PCh. 29 - Prob. 29.51PCh. 29 - Prob. 29.52PCh. 29 - Prob. 29.53PCh. 29 - Prob. 29.54PCh. 29 - Prob. 29.55PCh. 29 - Prob. 29.56PCh. 29 - Prob. 29.57PCh. 29 - Prob. 29.58PCh. 29 - Prob. 29.59PCh. 29 - 29-60 How does the energy source differ in...Ch. 29 - Prob. 29.61PCh. 29 - A vegan diet is one that excludes all animal...Ch. 29 - Prob. 29.63PCh. 29 - Prob. 29.64PCh. 29 - Prob. 29.65PCh. 29 - Prob. 29.66PCh. 29 - Prob. 29.67PCh. 29 - Prob. 29.68P
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- Consider this chemical reaction. What chemical is the oxidizing agent? COO™ HIC-H HIC-H FAD FADH₂ COO™ succinate FADH2 succinate FAD fumarate succinate dehydrogenase COO™ H-C -H COO fumaratearrow_forwardWhat class of enzymes to these two belong to?arrow_forwardIn the citric acid cycle, a - ketoglutarate dehydrogenase catalyzes the reaction from a - ketoglutarate to Succinyl CoA. Given this reaction, calculate for the enthalpy of formation of the product using (a) Hess's Law, (b) standard enthalpies of formation and (c) mean bond enthalpies. Show your complete solution. COA-S OOC CH2 CH2 + NAD++ COA + CO2 + NADH CH2 a-ketoglutarate CH2 dehydrogenase COO a-ketoglutarate COO Succinyl CoAarrow_forward
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- Mark any/all processes that are reductions. O FADH2 → FAD O hydrogenation of fats FAD FADH2 NAD* NADH NADH NAD*arrow_forwardThe rate-limiting step is a metabolic pathway is the slowest step which determines the overall rate of the other reactions in the pathway. In glycolysis, the rate limiting step is a phosphorylation reaction where phosphofructokinase (PFK-1) catalyzes the reaction fructose-6-bisphosphate -> fructose-1,6-bisphosphate, the same step in gluconeogenesis. Select one: The statement is FALSE. The statement is TRUE.arrow_forwardOne of the steps that occur during the synthesis of ketone bodies is shown below. OH D-beta-hydroxybutyrate Dehydrógenase .coo coo0 H3C cooo Нас acetoacetate D-beta-hydroxybutyrate Does this process require FAD or NAD*, FADH2 or NADH as the reactant coenzyme? Explain your answer in a few words.arrow_forward
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