Biology
12th Edition
ISBN: 9781260494570
Author: Raven, Peter
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 26, Problem 4S
Summary Introduction
To explain: The way through which a highly infectious strain of the virus that targets and destroys neurons might be changed so that it could deliver a gene to correct cystic fibrosis in lung tissue.
Introduction: Viruses are intracellular obligate
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Some retroviruses that have a wide host range have been developed for use in treatment of diseases or syndromes. These viruses do not result in a productive infection because they lack critical genes for viral
replication, but they do carry DNA sequences that allow them to be packaged into infectious particles. Once in the host cell the viral DNA is released and integrates into the cell's genome. The advantage to this
strategy is that the delivery of the DNA is very efficient. What is one possible problem of using a virus that can integrate into the human nuclear genome?
Multiple Choice
The virus carries genes that will interfere with host cell activities.
The viral DNA sequences could still cause a disease.
Since the viral DNA sequences no longer contain essential genes for viral replication the host cell may not be able to replicate either.
The integration could disrupt an essential gene or genes.
Which of the following is a known characteristic that can lead to genetic changes in some viruses?
Operons in the viral genome can undergo homologous recombination, leading to genetic rearrangements.
Reassortment of segmented genomes can occur if a host cell is co-infected with two different viral strains.
RNA polymerases used in replication of the viral genome have proofreading capability.
Environmental conditions can trigger the SOS response, which triggers mutations in the viral genome.
Which of the following are the functions of reverse transcriptase in retroviruses?
i) it hydrolyzes the host cell's DNA
ii) it uses viral RNA as a template for DNA synthesis
iii) it converts host cell RNA into viral DNA
iv) it translates viral RNA into proteins
v) It uses viral RNA as a template for making complementary RNA strand
vi) It degrades RNA from DNA-RNA hybrid
Oi, iv and v
O ii, iv, v and vi
ii and iii
ii and vi
Chapter 26 Solutions
Biology
Ch. 26.1 - Prob. 1LOCh. 26.1 - Prob. 2LOCh. 26.2 - Prob. 1LOCh. 26.2 - Prob. 2LOCh. 26.3 - Prob. 1LOCh. 26.3 - Describe how viruses can contribute DNA to their...Ch. 26.4 - Describe the differences between acute and...Ch. 26.4 - Prob. 2LOCh. 26.4 - Prob. 3LOCh. 26.5 - Prob. 1LO
Ch. 26 - Prob. 1UCh. 26 - Prob. 2UCh. 26 - Prob. 3UCh. 26 - Prob. 4UCh. 26 - Why is a drug that blocks HIV binding to one of...Ch. 26 - Prob. 6UCh. 26 - Prob. 7UCh. 26 - Prob. 1ACh. 26 - Prob. 2ACh. 26 - Prob. 3ACh. 26 - Prob. 4ACh. 26 - Prob. 5ACh. 26 - Prob. 6ACh. 26 - Prob. 7ACh. 26 - E. coli lysogens derived from infection by phage ...Ch. 26 - Prob. 2SCh. 26 - Prob. 3SCh. 26 - Prob. 4SCh. 26 - Prob. 5S
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- There have been recent outbreaks of dog flu in the US. Why doesn't this virus infect humans? A) The virus can replicate in cells of all species but can only egress from dog cells. B) The genetic code of the virus is the same as that in dog cells but is different from other organisms. C) The virus can only attach to dog cells. D) The virus can enter cells of all species but can only replicate in dog cells.arrow_forwardAs a general rule, viruses are not considered to be alive based on several reasons. One such reason is that some viruses use RNA as their genetic material instead of DNA. Which of the five biological themes does this violate? Briefly explain why.arrow_forwardA viral particle adsorbs onto a host cell membrane. It uncoats and releases its single-stranded nonsegmented nucleic acid into the cytoplasm where it is immed dependent RNA polymerase, into mRNA. It is then translated into viral structural proteins and enzymes. Which of the following virus families is most likely repre A) Herpesviridae B) Paramyxoviridae C) Parvoviridae D) Reovirius E) Retroviridaearrow_forward
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