To recommend a molecular basis for occurrence of idiosyncrasy (an unusual feature of a person) drug. The reason for taking precaution while giving other drugs to the patients those have a sensitivity to debrisoquine should be determined. Concept introduction: Debrisoquine is derived from guanidine. It is an antihypertensive drug which is alike to guanethidine. It is normally used for phenotyping the Cytochrome P4502D6 (CYP2D6) enzyme. It is a drug- metabolizing enzyme.

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Chapter 26, Problem 27P

Interpretation Introduction

Interpretation:

To recommend a molecular basis for occurrence of idiosyncrasy (an unusual feature of a person) drug. The reason for taking precaution while giving other drugs to the patients those have a sensitivity to debrisoquine should be determined.

Concept introduction:

Debrisoquine is derived from guanidine. It is an antihypertensive drug which is alike to guanethidine. It is normally used for phenotyping the Cytochrome P4502D6 (CYP2D6) enzyme. It is a drug-metabolizing enzyme.

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