ORGANIC CHEMISTRY-STUD.SOLNS.MAN+SG(LL)
ORGANIC CHEMISTRY-STUD.SOLNS.MAN+SG(LL)
4th Edition
ISBN: 9781119659587
Author: Klein
Publisher: WILEY
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Chapter 25.6, Problem 34PTS

(a)

Interpretation Introduction

Interpretation:

Synthesis of given set of dipeptides must be drawn with the reagents.

Concept introduction:

Peptides are a chain of amino acids that are linked together by amide bond.  The key steps involved in peptide synthesis is,

  • Installation of appropriate protecting groups in amino acid
  • Coupling of protected amino acids using DCC
  • Deprotection of protecting groups to give the final peptide.

To draw : To draw all steps and reagents for the synthesis of dipeptide Trp-Met

(b)

Interpretation Introduction

Interpretation:

Synthesis of given set of dipeptides must be drawn with the reagents.

Concept introduction:

Peptides are a chain of amino acids that are linked together by amide bond.  The key steps involved in peptide synthesis is,

  • Installation of appropriate protecting groups in amino acid
  • Coupling of protected amino acids using DCC
  • Deprotection of protecting groups to give the final peptide.

To draw : To draw all steps and reagents for the synthesis of dipeptide Ala-Ile

(c)

Interpretation Introduction

Interpretation:

Synthesis of given set of dipeptides must be drawn with the reagents.

Concept introduction:

Peptides are a chain of amino acids that are linked together by amide bond.  The key steps involved in peptide synthesis is,

  • Installation of appropriate protecting groups in amino acid
  • Coupling of protected amino acids using DCC
  • Deprotection of protecting groups to give the final peptide.

To draw : To draw all steps and reagents for the synthesis of dipeptide Leu-Val

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6. Consider the following exothermic reaction below. 2Cu2+(aq) +41 (aq)2Cul(s) + 12(aq) a. If Cul is added, there will be a shift left/shift right/no shift (circle one). b. If Cu2+ is added, there will be a shift left/shift right/no shift (circle one). c. If a solution of AgNO3 is added, there will be a shift left/shift right/no shift (circle one). d. If the solvent hexane (C6H14) is added, there will be a shift left/shift right/no shift (circle one). Hint: one of the reaction species is more soluble in hexane than in water. e. If the reaction is cooled, there will be a shift left/shift right/no shift (circle one). f. Which of the changes above will change the equilibrium constant, K?
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ORGANIC CHEMISTRY-STUD.SOLNS.MAN+SG(LL)

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