Organic Chemistry
Organic Chemistry
6th Edition
ISBN: 9781936221349
Author: Marc Loudon, Jim Parise
Publisher: W. H. Freeman
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Chapter 25, Problem 25.14P
Interpretation Introduction

(a)

Interpretation:

The elementary steps for the given transformation of a fatty acid into a fatty acyl-CoA are to be explained.

Concept introduction:

The transformation of a fatty acid into a fatty acyl-CoA is a two steps reaction. In the first step the fatty acid adenylated and in second step the nucleophilic attack of thiol group of coenzyme A convert it into fatty acyl-CoA.

Interpretation Introduction

(b)

Interpretation:

The additional reaction that ensures the completion of reaction of transformation of a fatty acid into a fatty acyl-CoA is to be determined.

Concept introduction:

The pyrophosphate formed in the first step of transformation of a fatty acid into a fatty acyl-CoA gets hydrolyzed to phosphate using magnesium.

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1. Calculate the accurate monoisotopic mass (using all 1H, 12C, 14N, 160 and 35CI) for your product using the table in your lab manual. Don't include the Cl, since you should only have [M+H]*. Compare this to the value you see on the LC-MS printout. How much different are they? 2. There are four isotopic peaks for the [M+H]* ion at m/z 240, 241, 242 and 243. For one point of extra credit, explain what each of these is and why they are present. 3. There is a fragment ion at m/z 184. For one point of extra credit, identify this fragment and confirm by calculating the accurate monoisotopic mass. 4. The UV spectrum is also at the bottom of your printout. For one point of extra credit, look up the UV spectrum of bupropion on Google Images and compare to your spectrum. Do they match? Cite your source. 5. For most of you, there will be a second chromatographic peak whose m/z is 74 (to a round number). For one point of extra credit, see if you can identify this molecule as well and confirm by…
Please draw, not just describe!
can you draw each step on a piece of a paper please this is very confusing to me
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