![Organic Chemistry](https://www.bartleby.com/isbn_cover_images/9781305080485/9781305080485_largeCoverImage.gif)
Interpretation:
The percentages of neutral and protonated forms present in a solution of 0.0010M pyrimidine at pH = 7.3 are to be calculated if the pKa of pyrimidinium ion is 1.3.
Concept introduction:
pH And pKa are related by Henderson-Hasselbalch equation as
Knowing pH and pKa values, the ratio between the two forms and from which their percentages can be determined.
To calculate:
The percentages of neutral and protonated forms present in a solution of 0.0010M pyrimidine at pH = 7.3, if the pKa of pyrimidinium ion is 1.3.
Answer:
At pH = 7.3, almost 100% pyrimidine molecules exist in the neutral form.
Explanation:
Deprotonation of the ammonium ion of a base can be represented as,
The Henderson-Hasselbalch can be written as
Substituting the values of pH and pKa, we get
Thus the concentration of neutral form is 106 times more than the protonated form. Hence almost 100% pyrimidine molecules exist in the neutral form.
Conclusion:
At pH = 7.3, almost 100% pyrimidine molecules exist in the neutral form.
![Check Mark](/static/check-mark.png)
Trending nowThis is a popular solution!
![Blurred answer](/static/blurred-answer.jpg)
Chapter 24 Solutions
Organic Chemistry
- Which one? Ca2^- Na2^+ Si2^+ Mg2^- AI2^-arrow_forwardIn general, which is more polar, the stationary phase or the mobile phase? The stationary phase is always more polar The mobile phase is always more polar It depends on our choices for both stationary and mobile phase Their polarity doesn't really matter so we never consider itarrow_forwardPlease helparrow_forward
- Draw the mechanism of aspirin synthesis in an basic medium and in a neutral medium, showing the attacks and the process for the formation of the product.arrow_forwardNa :S f. F NO2arrow_forwardQ1: For each molecule, assign each stereocenter as R or S. Circle the meso compounds. Label each compound as chiral or achiral. + CI OH woཡི།༠w Br H مه D CI ပ။ Br H, Br Br H₂N OMe R IN Ill N S H CI Br CI CI D OH H 1/111arrow_forward
- Chemistry: The Molecular ScienceChemistryISBN:9781285199047Author:John W. Moore, Conrad L. StanitskiPublisher:Cengage LearningChemistry by OpenStax (2015-05-04)ChemistryISBN:9781938168390Author:Klaus Theopold, Richard H Langley, Paul Flowers, William R. Robinson, Mark BlaserPublisher:OpenStax
![Text book image](https://www.bartleby.com/isbn_cover_images/9781285199047/9781285199047_smallCoverImage.gif)
![Text book image](https://www.bartleby.com/isbn_cover_images/9781938168390/9781938168390_smallCoverImage.gif)