
Concept explainers
Interpretation:
The synthesize of DL-leucine, DL-alanine, and DL-phenylalanine from potassium phthalimide and diethyl αa-bromomalonate.
Concept Introduction:
>Amino acids are synthesized by plants and animals. There are some amino acids which are not synthesized by the higher animals. These amino acids are then taken up by the animals from various other sources.
>There are two types of amino acid-syntheses, which are, from potassium phthalimide, and the Strecker synthesis. The potassium phthalimide type of synthesis uses diethyl αa-bromomalonate and SN2 reactions, and hydrolysis and decarboxylation occur in it.
>The potassium phthalimide method is a modification of the Gabriel synthesis of
Decarboxylation reaction is the reaction in which there is loss of a molecule of carbon dioxide from a compound.
>The reaction of an

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Chapter 24 Solutions
Organic Chemistry
- Synthesize 2-Ethyl-3-methyloxirane from dimethyl(propyl)sulfonium iodide using the necessary organic or inorganic reagents. Draw the structures of the compounds.arrow_forwardSynthesize 2-Hydroxy-2-phenylacetonitrile from phenylmethanol using the necessary organic or inorganic reagents. Draw the structures of the compounds.arrow_forwardSynthesize N-Methylcyclohexylamine from cyclohexanol using the necessary organic or inorganic reagents. Draw the structures of the compounds.arrow_forward
- Synthesize N-Methylcyclohexylamine from cyclohexanol using the necessary organic or inorganic reagents. Draw the structures of the compounds.arrow_forwardIf possible, please provide the formula of the compound 3,3-dimethylbut-2-enal.arrow_forwardSynthesize 1,4-dibromobenzene from acetanilide (N-phenylacetamide) using the necessary organic or inorganic reagents. Draw the structures of the compounds.arrow_forward
- Indicate the products obtained by mixing (3-oxo-3-phenylpropyl)triphenylphosphonium bromide with sodium hydride.arrow_forwardWe mix N-ethyl-2-hexanamine with excess methyl iodide and followed by heating with aqueous Ag2O. Indicate the major products obtained.arrow_forwardIndicate the products obtained by mixing acetophenone with iodine and NaOH.arrow_forward
- Indicate the products obtained by mixing 2-Propanone and ethyllithium and performing a subsequent acid hydrolysis.arrow_forwardIndicate the products obtained if (E)-2-butenal and 3-oxo-butanenitrile are mixed with sodium ethoxide in ethanol.arrow_forwardQuestion 3 (4 points), Draw a full arrow-pushing mechanism for the following reaction Please draw all structures clearly. Note that this intramolecular cyclization is analogous to the mechanism for halohydrin formation. COH Br + HBr Brarrow_forward
