The heptapeptide sequence of amino acids, on the basis of the information provided, is to be deduced. Concept introduction: On treating a polypeptide with 2,4-dinitrofluorobenzene in basic solution, the free amino group of the N-terminal gives a nucleophilic aromatic substitution reaction, which, on hydrolysis, gives a mixture of amino acids in which the N-terminal amino acid is labeled with a 2,4-dinitrophenyl group. The C-terminal residues are identified through the carboxypeptidase enzymes. These enzymes catalyze the hydrolysis of the amide bond of the amino acid residue containing a free liberating carboxylic acid group.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 24, Problem 23P

Interpretation Introduction

Interpretation:

The heptapeptide sequence of amino acids, on the basis of the information provided, is to be deduced.

Concept introduction:

On treating a polypeptide with 2,4-dinitrofluorobenzene in basic solution, the free amino group of the N-terminal gives a nucleophilic aromatic substitution reaction, which, on hydrolysis, gives a mixture of amino acids in which the N-terminal amino acid is labeled with a 2,4-dinitrophenyl group. The C-terminal residues are identified through the carboxypeptidase enzymes. These enzymes catalyze the hydrolysis of the amide bond of the amino acid residue containing a free liberating carboxylic acid group.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Give detailed mechanism Solution with explanation needed. Don't give Ai generated solution

Show work with explanation needed....don't give Ai generated solution

1. 6. Draw the products for the following reaction: 2. Diels-Aider reaction NOH O OH

Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 24, Problem 23P

Interpretation Introduction

Interpretation:

The heptapeptide sequence of amino acids, on the basis of the information provided, is to be deduced.

Concept introduction:

On treating a polypeptide with 2,4-dinitrofluorobenzene in basic solution, the free amino group of the N-terminal gives a nucleophilic aromatic substitution reaction, which, on hydrolysis, gives a mixture of amino acids in which the N-terminal amino acid is labeled with a 2,4-dinitrophenyl group. The C-terminal residues are identified through the carboxypeptidase enzymes. These enzymes catalyze the hydrolysis of the amide bond of the amino acid residue containing a free liberating carboxylic acid group.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 24, Problem 23P

Interpretation Introduction

Interpretation:

The heptapeptide sequence of amino acids, on the basis of the information provided, is to be deduced.

Concept introduction:

On treating a polypeptide with 2,4-dinitrofluorobenzene in basic solution, the free amino group of the N-terminal gives a nucleophilic aromatic substitution reaction, which, on hydrolysis, gives a mixture of amino acids in which the N-terminal amino acid is labeled with a 2,4-dinitrophenyl group. The C-terminal residues are identified through the carboxypeptidase enzymes. These enzymes catalyze the hydrolysis of the amide bond of the amino acid residue containing a free liberating carboxylic acid group.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 24, Problem 23P

Interpretation Introduction