Organic Chemistry
Organic Chemistry
12th Edition
ISBN: 9781118875766
Author: T. W. Graham Solomons, Craig B. Fryhle, Scott A. Snyder
Publisher: WILEY
Question
Book Icon
Chapter 24, Problem 2LGP
Interpretation Introduction

Interpretation:

Notes for a class presentation on the mechanism of chymotrypsin are to be prepared by considering the role of catalytic triad with regard to acid–base catalysis and the relative propensity of various groups.

Concept introduction:

Pancreatic enzymes involved in the hydrolysis of peptide bonds are generally calledserine proteases because their enzymatic activity involve a serine residue. Chymotrypsin is a pancreatic enzyme that is involved in the hydrolysis of peptide bonds.

Blurred answer
Students have asked these similar questions
Treatment of a new protein with dansyl chloride reveals two (2) dansyl-labelled derivatives of amino acids, alanine and methionine. What can you deduce about the structure of the proteinfrom these results?
Amylase’ is an enzyme in our saliva that digests the ‘amylose’ protein in mouth. How could you justify the mechanism of enzymatic action using enzyme-catalyzed reaction models?
The activity of an enzyme requires a glutamic acid to display its -COOH functional group in the protonated state. Suppose the pK, of the -COOH group is 4.07. (a) Will the enzyme be more active at pH 3.5 or 4.5? Explain. (b) What fraction of the enzymes will be active at pH = 4.07? Explain. (c) At what pH will the enzyme show 78% of maximal activity?
Knowledge Booster
Background pattern image
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Organic Chemistry
Chemistry
ISBN:9781305080485
Author:John E. McMurry
Publisher:Cengage Learning
Text book image
Chemistry: Principles and Reactions
Chemistry
ISBN:9781305079373
Author:William L. Masterton, Cecile N. Hurley
Publisher:Cengage Learning
Text book image
Organic Chemistry
Chemistry
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:Cengage Learning
Text book image
Chemistry for Today: General, Organic, and Bioche...
Chemistry
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Cengage Learning