
Interpretation:
The steps involved in the synthesis of the tripeptide KFA using the SPPS procedure are to be outlined.
Concept introduction:
Amino acids are organic compounds containing
Basicity is the ability to donate electron pair. Compounds that can donate electron pair easily are more basic.
In solid-phase peptide synthesis (SPPS), peptides are prepared, residue by residue; one end of the peptide is anchored to an insoluble
Diisopropylcarbodiimide is used as a bond forming agent between N-terminal amino acid of the peptide growing and carbonyl group of the new amino acid.
Fmoc is the protection group used in the synthesis of polypeptides by solid phase peptide synthesis.
Boc and Phenyl-Fmoc are the protection groups that are used for protecting side-chain amino group.

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Chapter 24 Solutions
Organic Chemistry
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- Indicate the products obtained by mixing 2-Propanone and ethyllithium and performing a subsequent acid hydrolysis.arrow_forwardIndicate the products obtained if (E)-2-butenal and 3-oxo-butanenitrile are mixed with sodium ethoxide in ethanol.arrow_forwardQuestion 3 (4 points), Draw a full arrow-pushing mechanism for the following reaction Please draw all structures clearly. Note that this intramolecular cyclization is analogous to the mechanism for halohydrin formation. COH Br + HBr Brarrow_forward
- Chemistry: The Molecular ScienceChemistryISBN:9781285199047Author:John W. Moore, Conrad L. StanitskiPublisher:Cengage Learning

