Organic Chemistry (8th Edition)
8th Edition
ISBN: 9780134042282
Author: Paula Yurkanis Bruice
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 23, Problem 28P
When transaminated, the three branched-chain amino acids (valine, leucine, and isoleucine) form compounds that have the characteristic odor of maple syrup. An enzyme known as branched-chain α-keto acid dehydrogenase converts these compounds into CoA esters. People who do not have this enzyme have the genetic disease known as maple syrup urine disease, so called because their urine smells like maple syrup.
- a. Draw the compounds that smell like maple syrup.
- b. Draw the CoA esters.
- c. Branched-chain α-keto acid dehydrogenase has live coenzymes. Identify them.
- d. Suggest a way to treat maple syrup urine disease.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Find a molecular formula for these unknowns
(ME EX2) Prblms 8-11 Can you please explain problems 8 -11 to me in detail, step by step? Thank you so much! If needed color code them for me.
Don't used hand raiting
Chapter 23 Solutions
Organic Chemistry (8th Edition)
Ch. 23.1 - Prob. 2PCh. 23.1 - Prob. 3PCh. 23.2 - How many conjugated double bonds are there in a....Ch. 23.2 - Instead of adding to the 4a position and...Ch. 23.2 - Prob. 7PCh. 23.3 - Prob. 8PCh. 23.3 - Acetolactate synthase is another TPP-requiring...Ch. 23.3 - Acetolactate synthase transfers the acyl group of...Ch. 23.3 - Prob. 12PCh. 23.5 - Which compound is more easily decarboxylated?
Ch. 23.5 - Prob. 14PCh. 23.5 - Explain why the ability of PLP to catalyze an...Ch. 23.5 - Explain why the ability of PLP to catalyze an...Ch. 23.5 - The enzyme that catalyzes the C C bond cleavage...Ch. 23.5 - Propose a mechanism for the ,-elimination reaction...Ch. 23.6 - Ethanolamine ammonia lyase, a coenzyme...Ch. 23.6 - Prob. 20PCh. 23.7 - How do the structure of tetrahydrofolate and...Ch. 23.7 - What is the source of the methyl group in...Ch. 23.8 - Thiols such as ethanethiol and propanethiol can be...Ch. 23 - How does the metal ion in carboxypeptidase A...Ch. 23 - Prob. 24PCh. 23 - Prob. 25PCh. 23 - For each of the following reactions, name both the...Ch. 23 - Prob. 27PCh. 23 - When transaminated, the three branched-chain amino...Ch. 23 - What acyl groups have we seen transferred by...Ch. 23 - Propose a mechanism for the following reaction:Ch. 23 - Draw the products of the following reaction, where...Ch. 23 - When UMP is dissolved in T2O, exchange of T for H...Ch. 23 - Dehydratase is a PLP-requiring enzyme that...Ch. 23 - In addition to the reaction mentioned in Section...Ch. 23 - PLP can catalyze both ,-elimination reactions...Ch. 23 - The glycine cleavage system is a group of four...Ch. 23 - Prob. 37PCh. 23 - FADH2 reduces , -unsaturated thioesters to...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Similar questions
- The following 'H NMR spectrum was taken with a 750 MHz spectrometer: 1.0 0.5 0.0 10.0 9.0 8.0 7.0 6.0 5.0 4.0 3.0 ' 2.0 1.0 0.0 (ppm) What is the difference Av in the frequency of RF ac Δν ac radiation absorbed by the a and c protons? (Note: it's not equal to the difference in chemical shifts.) Round your answer to 2 significant digits, and be sure it has an appropriate unit symbol. = O O a will shift left, c will shift right. O a will shift right, c will shift left. a and c will both shift left, with more space between them. Suppose a new spectrum is taken with a 500 MHz spectrometer. What will be true about this new spectrum? O a and c will both shift left, with less space between them. O a and c will both shift right, with more space between them. O a and c will both shift right, with less space between them. Which protons have the largest energy gap between spin up and spin down states? O None of the above. ○ a Ob Explanation Check C Ar B 2025 McGraw Hill LLC. All Rights Reserved.…arrow_forwardWhat mass of Na2CO3 must you add to 125g of water to prepare 0.200 m Na2CO3? Calculate mole fraction of Na2CO3, mass percent, and molarity of the resulting solution. MM (g/mol): Na2CO3 105.99; water 18.02. Final solution density is 1.04 g/mL.arrow_forward(ME EX2) Prblms Can you please explain problems to me in detail, step by step? Thank you so much! If needed color code them for me.arrow_forward
- Experiment #8 Electrical conductivity & Electrolytes. Conductivity of solutions FLINN Scientific Scale RED LED Green LED LED Conductivity 0 OFF OFF 1 Dim OFF 2 medium OFF 3 Bright Dim Low or Nowe Low Medium High 4 Very Bright Medium nd very high AA Δ Δ Δ Δ Δ Δ Δ Δ Δ Δ Δ SE=Strong Electrolyte, FE = Fair Electrolyte CWE = Weak Electrolyte, NE= Noni Electrolyte, #Solutions 1 0.1 M NaCl 2/1x 102 M NaCl, 3/1X103 M Nall Can Prediction M Observed Conductivity Very bright red Bright red Dim red you help me understand how I'm supposed to find the predictions of the following solutions? I know this is an Ionic compound and that the more ions in a solution means it is able to carry a charge, right? AAAA Darrow_forward(SE EX 2) Prblsm 4-7: Can you please explain problems 4-7 and color code if needed for me. (step by step) detail explanationsarrow_forward(SE EX 2) Problems 8-11, can you please explain them to me in detail and color-code anything if necessary?arrow_forward
- (ME EX2) Problems 15-16 Could you please explain problems 15 through 16 to me in detail, step by step? Thank you so much! If necessary, please color-code them for me.arrow_forward1.)show any electrophilic aromatic substitution, identify the electriphile, nucleophile and transition statearrow_forward(SE EX 2) Problems 15-16, can you please explain them to me in detail and color-code anything if necessary?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
General, Organic, and Biological ChemistryChemistryISBN:9781285853918Author:H. Stephen StokerPublisher:Cengage Learning
Organic And Biological ChemistryChemistryISBN:9781305081079Author:STOKER, H. Stephen (howard Stephen)Publisher:Cengage Learning,
Chemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage Learning
Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage Learning
Introductory Chemistry: A FoundationChemistryISBN:9781337399425Author:Steven S. Zumdahl, Donald J. DeCostePublisher:Cengage Learning
General, Organic, and Biological Chemistry
Chemistry
ISBN:9781285853918
Author:H. Stephen Stoker
Publisher:Cengage Learning
Organic And Biological Chemistry
Chemistry
ISBN:9781305081079
Author:STOKER, H. Stephen (howard Stephen)
Publisher:Cengage Learning,
Chemistry for Today: General, Organic, and Bioche...
Chemistry
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Cengage Learning
Introduction to General, Organic and Biochemistry
Chemistry
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Cengage Learning
Introductory Chemistry: A Foundation
Chemistry
ISBN:9781337399425
Author:Steven S. Zumdahl, Donald J. DeCoste
Publisher:Cengage Learning
Lipids - Fatty Acids, Triglycerides, Phospholipids, Terpenes, Waxes, Eicosanoids; Author: The Organic Chemistry Tutor;https://www.youtube.com/watch?v=7dmoH5dAvpY;License: Standard YouTube License, CC-BY