The synthesis of N-methyl-4-phenyl-piperidine that shows the necesaary reagents and isolated intermediates is to be shown. Concept introduction: The general steps involved in the formation of alcohol from ester are as follows. The first step is the nucleophilic attack of first equivalent of Grignard reagent. The second step involves the removal of the leaving group. The next step is the nucleophilic attack of second equivalent of Grignard reagent. The last step is the protonation of the intermediate formed above.

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Answer 1

Question

Chapter 22, Problem 52P

Interpretation Introduction

Interpretation:

The synthesis of N-methyl-4-phenyl-piperidine that shows the necesaary reagents and isolated intermediates is to be shown.

Concept introduction:

The general steps involved in the formation of alcohol from ester are as follows.

The first step is the nucleophilic attack of first equivalent of Grignard reagent.

The second step involves the removal of the leaving group.

The next step is the nucleophilic attack of second equivalent of Grignard reagent.

The last step is the protonation of the intermediate formed above.

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Answer 2

Question

Chapter 22, Problem 52P

Interpretation Introduction

Interpretation:

The synthesis of N-methyl-4-phenyl-piperidine that shows the necesaary reagents and isolated intermediates is to be shown.

Concept introduction:

The general steps involved in the formation of alcohol from ester are as follows.

The first step is the nucleophilic attack of first equivalent of Grignard reagent.

The second step involves the removal of the leaving group.

The next step is the nucleophilic attack of second equivalent of Grignard reagent.

The last step is the protonation of the intermediate formed above.

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Answer 3

Question

Chapter 22, Problem 52P

Interpretation Introduction

Interpretation:

The synthesis of N-methyl-4-phenyl-piperidine that shows the necesaary reagents and isolated intermediates is to be shown.

Concept introduction:

The general steps involved in the formation of alcohol from ester are as follows.

The first step is the nucleophilic attack of first equivalent of Grignard reagent.

The second step involves the removal of the leaving group.

The next step is the nucleophilic attack of second equivalent of Grignard reagent.

The last step is the protonation of the intermediate formed above.

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Answer 4

Question

Chapter 22, Problem 52P

Interpretation Introduction

Interpretation:

The synthesis of N-methyl-4-phenyl-piperidine that shows the necesaary reagents and isolated intermediates is to be shown.

Concept introduction:

The general steps involved in the formation of alcohol from ester are as follows.

The first step is the nucleophilic attack of first equivalent of Grignard reagent.

The second step involves the removal of the leaving group.

The next step is the nucleophilic attack of second equivalent of Grignard reagent.

The last step is the protonation of the intermediate formed above.

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Answer 5

Chapter 22, Problem 52P

Interpretation Introduction

Interpretation:

The synthesis of N-methyl-4-phenyl-piperidine that shows the necesaary reagents and isolated intermediates is to be shown.

Concept introduction:

The general steps involved in the formation of alcohol from ester are as follows.

The first step is the nucleophilic attack of first equivalent of Grignard reagent.

The second step involves the removal of the leaving group.

The next step is the nucleophilic attack of second equivalent of Grignard reagent.

The last step is the protonation of the intermediate formed above.

Answer 6

Chapter 22, Problem 52P

Interpretation Introduction

Interpretation:

The synthesis of N-methyl-4-phenyl-piperidine that shows the necesaary reagents and isolated intermediates is to be shown.

Concept introduction:

The general steps involved in the formation of alcohol from ester are as follows.

The first step is the nucleophilic attack of first equivalent of Grignard reagent.

The second step involves the removal of the leaving group.

The next step is the nucleophilic attack of second equivalent of Grignard reagent.

The last step is the protonation of the intermediate formed above.

Answer 7

Chapter 22, Problem 52P

Interpretation Introduction

Interpretation:

The synthesis of N-methyl-4-phenyl-piperidine that shows the necesaary reagents and isolated intermediates is to be shown.

Concept introduction:

The general steps involved in the formation of alcohol from ester are as follows.

The first step is the nucleophilic attack of first equivalent of Grignard reagent.

The second step involves the removal of the leaving group.

The next step is the nucleophilic attack of second equivalent of Grignard reagent.

The last step is the protonation of the intermediate formed above.

Answer 8

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Answer 9

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Answer 10

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Answer 11

Ch. 22.1 - Prob. 1P Ch. 22.1 - Prob. 2P Ch. 22.1 - Prob. 3P Ch. 22.2 - Prob. 4P Ch. 22.4 - Prob. 5P Ch. 22.4 - Prob. 6P Ch. 22.4 - Prob. 7P Ch. 22.4 - Prob. 8P Ch. 22.4 - Prob. 9P Ch. 22.7 - Prob. 10P

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Chapter 22 Solutions