Concept explainers
To determine: Whether the people with HLA-B*51 are more or less likely than those with other HLAs to have the virus with the mutation.
Introduction: Human immunodeficiency virus (HIV) is the group of retrovirus that is sexually transmitted from one to another. It causes a disease that leads to life-threatening infections called AIDS. Here, the immune system fails or weakens due to the viral infection and is accompanied with the development of many infections. Certain proteins called human leukocyte antigen (HLA) are produced and displayed by our cells that act as a marker for the identification of unusual invaders in the body. Each unique marker is produced for the determination of self-cells versus the invaders by the immune system.
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