If left untreated, most HIV-infected individuals will develop AIDS. Current treatments are focused on highlyactive antiretroviral therapy (HAART). HAART usually consists of an orally delivered drug cocktail containingtwo different reverse transcriptase inhibitors and one other drug, such as a protease inhibitor. Question: Develop a pharmacokinetic model of HAART treatment. Consider all 3 drugs. Make sure to include adiagram that illustrates your thinking, state all assumptions, and define your variables. Whatparameters would you need to know to find the concentration of drug in the plasma? In the T cells?(You do not need to write out or solve any equations.)
If left untreated, most HIV-infected individuals will develop AIDS. Current treatments are focused on highlyactive antiretroviral therapy (HAART). HAART usually consists of an orally delivered drug cocktail containingtwo different reverse transcriptase inhibitors and one other drug, such as a protease inhibitor. Question: Develop a pharmacokinetic model of HAART treatment. Consider all 3 drugs. Make sure to include adiagram that illustrates your thinking, state all assumptions, and define your variables. Whatparameters would you need to know to find the concentration of drug in the plasma? In the T cells?(You do not need to write out or solve any equations.)
Chapter6: Oral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 2.3P
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If left untreated, most HIV-infected individuals will develop AIDS. Current treatments are focused on highly
active antiretroviral therapy (HAART). HAART usually consists of an orally delivered drug cocktail containing
two different reverse transcriptase inhibitors and one other drug, such as a protease inhibitor.
Question: Develop a pharmacokinetic model of HAART treatment. Consider all 3 drugs. Make sure to include a
diagram that illustrates your thinking, state all assumptions, and define your variables. What
parameters would you need to know to find the concentration of drug in the plasma? In the T cells?
(You do not need to write out or solve any equations.)
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