ORGANIC CHEMISTRY-PACKAGE >CUSTOM<
ORGANIC CHEMISTRY-PACKAGE >CUSTOM<
10th Edition
ISBN: 9781260028355
Author: Carey
Publisher: MCG CUSTOM
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Chapter 18.4, Problem 4P
Interpretation Introduction

Interpretation: It is to be identified if catalytic hydrogenation can be used to reduce a carboxylic acid to a primary alcohol in the first step of the sequence RCO2HRCH2OHRCHO.

Concept introduction: The addition of H2 to a molecule in the presence of a catalyst is known as catalytic hydrogenation reaction. This process is used to reduce aldehydes and ketones to alcohols.

Lithium aluminum hydride and sodium borohydride are strong reducing agents. They are inorganic compounds which are used as the reducing agents in organic synthesis. They used for the conversion of carboxylic acids, aldehydes and ketones into primary and secondary alcohols.

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Predict the reactants used in the formation of the following compounds using Acid-Catalyzed dehydration reaction
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.. Give the major organic product(s) for each of the following reactions or sequences of reactions. Show ll relevant stereochemistry [3 ONLY]. A H Br 1. NaCN 2 NaOH, H₂O, heat 3. H3O+ B. CH₂COOH 19000 1. LiAlH4 THF, heat 2 H₂O* C. CH Br 1. NaCN, acetone 2 H3O+, heat D. Br 1. Mg. ether 3. H₂O+ 2 CO₂ E. CN 1. (CH) CHMgBr, ether 2 H₂O+

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