Chapter 18, Problem 8P

a.	Describe two ways you could potentially make a transgene that would inhibit the function of a specific gene in a transgenic organism. (Hint: For one of these techniques, recall the discussion of RNA interference in Chapter 17.)
b.	Discuss how you could use either of these methods to construct a mouse model for a recessive human genetic condition associated with a loss of function, such as cystic fibrosis.