Organic Chemistry
11th Edition
ISBN: 9781118133576
Author: T. W. Graham Solomons, Craig Fryhle
Publisher: Wiley, John & Sons, Incorporated
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Chapter 18, Problem 4Q
Interpretation Introduction
Interpretation:
The preferred base for the alkylation of monoalkylacetoacetic ester is to be identified.
Concept introduction:
The acetoacetic ester is a
In monoalkylacetoacetic ester, a second alkylation also takes place, due to thepresence of an acidic hydrogen, in the presence of stronger base.
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Rank the compounds in each group below according to their reactivity toward electrophilic aromatic
substitution (most reactive = 1; least reactive = 3). Place the number corresponding to the compounds'
relative reactivity in the blank below the compound.
a.
CH₂F
CH3
F
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:0:
C-O
phenyl benzoate
6.Consider the reaction below to answer the following questions.
A
B
C
NO₂
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+
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D
a.
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BODADES
b. The Lewis acid catalyst in the reaction is:
C.
This reaction proceeds
d. Draw the structure of product D.
(faster or slower) than benzene.
Part 2. A solution of 6.00g of substance B in 100.0mL of aqueous solution is in equilibrium, at room temperature,
wl a solution of B in diethyl ether (ethoxyethane) containing 25.0 g of B in 50.0 mL
9) what is the distribution coefficient of substance B
b) what is
the mass of B extracted by shaking 200 ml of an aqueous solution containing
10g of B with call at room temp):
i) 100 mL of
diethyl ether
ii) 50ml of diethyl ether twice
iii) 25ml of diethyl ether four times
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a.
NO₂
NO₂
CH2CH2CH2CH2OH
CH3 CH3CH2CHOH
CH3CH2CH2CH2OH
NO₂
CH3CHCH2CH2OH
b.
OH
OH
CH₂OH
CO₂H
HC
CN
CN
CN
Chapter 18 Solutions
Organic Chemistry
Ch. 18 - Prob. 1PPCh. 18 - Practice Problem 18.2 Would optically active...Ch. 18 - Prob. 3PPCh. 18 - Practice Problem 18.4 Why do we say that the...Ch. 18 - Prob. 5PPCh. 18 - Practice Problem 18.6 (a) Write a reaction...Ch. 18 - PRACTICE PROBLEM 18.7
Show how you would use the...Ch. 18 - Practice Problem 18.8 The acetoacetic ester...Ch. 18 - Practice Problem 18.9
In the synthesis of the keto...Ch. 18 - PRACTICE PROBLEM 18.10 How would you use the...
Ch. 18 - PRACTICE PROBLEM 18.11
How would you use the...Ch. 18 - PRACTICE PROBLEM 18.12 Outline all steps in a...Ch. 18 - PRACTICE PROBLEM 18.13
The antiepileptic drug...Ch. 18 - PRACTICE PROBLEM 18.14 Show how you could employ...Ch. 18 - Prob. 15PCh. 18 - Treating a solution of cis-1-decalone with base...Ch. 18 - Prob. 17PCh. 18 - Prob. 18PCh. 18 - Prob. 19PCh. 18 - Prob. 20PCh. 18 - Prob. 21PCh. 18 - Prob. 22PCh. 18 - Prob. 23PCh. 18 - The synthesis of cyclobutanecarboxylic acid given...Ch. 18 - Prob. 25PCh. 18 - Prob. 26PCh. 18 - Prob. 27PCh. 18 - Prob. 28PCh. 18 - Compound J, a compound with two four-membered...Ch. 18 - Prob. 30PCh. 18 - Prob. 31PCh. 18 - 18.32 Shown below is a synthesis of the elm bark...Ch. 18 - 18.33 (a) A compound U gives a negative iodoform...Ch. 18 - 18.34 Compound A has the molecular formula and...Ch. 18 - Prob. 35PCh. 18 - 1. -Carotene is a highly conjugated hydrocarbon...Ch. 18 - Dehydroabietic acid is a natural product isolated...Ch. 18 - Prob. 1QCh. 18 - Prob. 2QCh. 18 - Prob. 3QCh. 18 - Prob. 4QCh. 18 - Prob. 5Q
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