Biochemistry
9th Edition
ISBN: 9781305961135
Author: Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher: Cengage Learning
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 17, Problem 34RE
BIOCHEMICAL CONNECTIONS Beriberi is a disease caused by a deficiency of vitamin B1 (thiamine) in the diet. Thiamine is the precursor of thiamine pyrophosphate. In view of what you have learned in this chapter, why is it not surprising that alcoholics tend to develop this disease?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionChapter 17 Solutions
Biochemistry
Ch. 17 - RECALL Which reaction or reactions that we have...Ch. 17 - RECALL Which reaction or reactions that we have...Ch. 17 - RECALL What are the possible metabolic fates of...Ch. 17 - RECALL Explain the origin of the name of the...Ch. 17 - RECALL Define isozymes and give an example from...Ch. 17 - RECALL Why would enzymes be found as isozymes?Ch. 17 - RECALL Why is the formation of...Ch. 17 - REFLECT AND APPLLY Show that the reaction...Ch. 17 - REFLECT AND APPLLY What is the metabolic advantage...Ch. 17 - REFLECT AND APPLLY What are the metabolic effects...
Ch. 17 - REFLECT AND APPLLY In what way is the observed...Ch. 17 - REFLECT AND APPLLY How does ATP act as an...Ch. 17 - RECALL At what point in glycolysis are all the...Ch. 17 - RECALL Which of the enzymes discussed in this...Ch. 17 - RECALL Define substrate-level phosphorylation and...Ch. 17 - Prob. 16RECh. 17 - RECALL Which molecules act as inhibitors of...Ch. 17 - RECALL Many NADH-linked dehydrogenases have...Ch. 17 - RECALL Several of the enzymes of glycolysis fall...Ch. 17 - Prob. 20RECh. 17 - REFLECT AND APPLLY Is the reaction of...Ch. 17 - Prob. 22RECh. 17 - Prob. 23RECh. 17 - Prob. 24RECh. 17 - Prob. 25RECh. 17 - Prob. 26RECh. 17 - Prob. 27RECh. 17 - Prob. 28RECh. 17 - RECALL If lactic acid is the buildup product of...Ch. 17 - Prob. 30RECh. 17 - Prob. 31RECh. 17 - Prob. 32RECh. 17 - REFLECT AND APPLLY What is unique about TPP that...Ch. 17 - BIOCHEMICAL CONNECTIONS Beriberi is a disease...Ch. 17 - REFLECT AND APPLLY Most hunters know that meat...Ch. 17 - REFLECT AND APPLLY What is the metabolic advantage...Ch. 17 - BIOCHEMICAL CONNECTIONS Cancer cells grow so...Ch. 17 - Prob. 38RECh. 17 - Prob. 39RECh. 17 - REFLECT AND APPLLY Show how the estimate of 33%...Ch. 17 - Prob. 41RECh. 17 - Prob. 42RECh. 17 - Prob. 43RECh. 17 - Prob. 44RECh. 17 - REFLECT AND APPLLY Show, by a series of equations,...Ch. 17 - REFLECT AND APPLLY What should be the net ATP...Ch. 17 - Prob. 47RECh. 17 - Prob. 48RECh. 17 - Prob. 49RECh. 17 - REFLECT AND APPLLY According to Table 17.1,...Ch. 17 - Prob. 51RECh. 17 - Prob. 52RECh. 17 - REFLECT AND APPLLY High levels of...Ch. 17 - Prob. 54RECh. 17 - Prob. 55RE
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Similar questions
- REFLECT AND APPLY Explain why a 50S ribosomal subunit and a 30S ribosomal subunit combine to form a 70S subunit, instead of an 80S subunit.arrow_forwardREFLECT AND APPLY A researcher claims to have discovered a variant form of glycogen. The variation is that it has very few branches (every 50 glucose residues or so) and that the branches are only three residues long. Is it likely that this discovery will be confirmed by later work?arrow_forwardREFLECT AND APPLY A mutation that changes an alanine residue in a protein to an isoleucine leads to a loss of activity. Activity is regained when a further mutation at the same site changes the isoleucine to a glycine. Why?arrow_forward
- REFLECT AND APPLY The enzyme D-amino acid oxidase has a very high turnover number because the D-amino acids are potentially toxic. The KM for the enzyme is in the range of 1 to 2 mM for the aromatic amino acids and in the range of 15 to 20 mM for such amino acids as serine, alanine, and the acidic amino acids. Which of these amino acids are the preferred substrates for the enzyme?arrow_forwardREFLECT AND APPLY Consider the structures of arabinose and ribose. Explain why nucleotide derivatives of arabinose, such as ara-C and ara-A, are effective metabolic poisons.arrow_forwardREFLECT AND APPLY The process of protein folding is spontaneous in the thermodynamic sense. It gives rise to a highly ordered conformation that has a lower entropy than the unfolded protein. How can this be?arrow_forward
- REFLECT AND APPLY You are in the process of determining the amino acid sequence of a protein and must reconcile contradictory results. In one trial, you determine a sequence with glycine as the N-terminal amino acid and asparagine as the C-terminal amino acid. In another trial, your results indicate phenylalanine as the N-terminal amino acid and alanine as the C-terminal amino acid. How do you reconcile this apparent contradiction?arrow_forwardREFLECT AND APPLLY What are the metabolic effects of not being able to produce the M subunit of phosphofructokinase?arrow_forwardREFLECT AND APPLY Pectin, which occurs in plant cell walls, exists in nature as a polymer of D-galacturonic acid methylated at car- bon 6 of the monomer. Draw a Haworth projection for a repeating disaccharide unit of pectin with one methylated and one unmeth- ylated monomer unit in (14) linkage.arrow_forward
- REFLECT AND APPLY Suggest a reason why the cell membranes of bacteria grown at 20C tend to have a higher proportion of unsaturated fatty acids than the membranes of bacteria of the same species grown at 37C. In other words, the bacteria grown at 37C have a higher proportion of saturated fatty acids in their cell membranes.arrow_forwardREFLECT AND APPLY In prokaryotic protein synthesis, N-formylmethionine (fmet) is the first amino acid incorporated, whereas (normal) methionine is incorporated in eukaryotes. The same codon (AUG) serves both. What prevents methionine from being inserted into the beginning and N-formylmethionine in the interior?arrow_forwardRECALL Why can we say that production of a GTP is equivalent to production of an ATP?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Biomolecules - Protein - Amino acids; Author: Tutorials Point (India) Ltd.;https://www.youtube.com/watch?v=ySNVPDHJ0ek;License: Standard YouTube License, CC-BY